小儿僵人综合征伴肾衰竭
Pediatric stiff-person syndrome with renal failure.
作者信息
Kumar M Veerendra, Savida P
机构信息
Department of Pediatrics, Government Medical College, Kottayam, Kerala, India.
出版信息
J Neurosci Rural Pract. 2016 Jan-Mar;7(1):147-9. doi: 10.4103/0976-3147.165352.
Abstract
Stiff-person syndrome (SPS) is an autoimmune neuronitis with progressive myoclonus and stiffness. It is a rare but treatable disorder with few case reports in children. SPS is due to autoantibodies against the enzyme glutamic acid decarboxylase which is present in neuronal and nonneuronal tissues. This is the case report of an 8-year-old boy with clinical and investigational features suggestive of SPS with associated myoglobin-induced renal failure, who completely recovered with treatment.
摘要
僵人综合征（SPS）是一种伴有进行性肌阵挛和僵硬的自身免疫性神经炎。它是一种罕见但可治疗的疾病，儿童病例报告较少。SPS是由针对存在于神经元和非神经元组织中的谷氨酸脱羧酶的自身抗体引起的。本文报告了一名8岁男孩，其临床和检查特征提示为SPS并伴有肌红蛋白诱导的肾衰竭，经治疗后完全康复。
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