Gasser P
Department of Internal Medicine, St. Claraspital, Basle, Switzerland.
Int Ophthalmol. 1989 Jul;13(4):281-90. doi: 10.1007/BF02280088.
The typical morphological and consequent functional damage caused by disease entities covered by the term 'glaucoma' is the result of inadequate circulation to the optic nerve fibres, predominantly in the papillary region, as a result of elevated intraocular pressure. The aim of this study is classification of different forms of glaucoma on the basis of blood flow parameters. Physiological and pathophysiological aspects of ocular blood flow and of microcirculation and hemorrheology will be considered and the significance of ocular vasospasm in low-tension glaucoma discussed. The frequent occurrence of vasospasm in the nailfold capillaries and of visual field deterioration after a cold-water test demonstrates that vasospasm is an expression of different underlying phenomena. Our results show that, in patients with ocular vasospasm, treatment with a calcium antagonist brings about a clear reversal of their visual field defects.
术语“青光眼”所涵盖的疾病实体所导致的典型形态学及随之而来的功能损害，是由于眼内压升高致使视神经纤维，主要是视乳头区域的视神经纤维循环不足所致。本研究的目的是基于血流参数对不同类型的青光眼进行分类。将考虑眼血流、微循环和血液流变学的生理和病理生理方面，并讨论眼血管痉挛在低眼压青光眼中的意义。甲襞毛细血管中频繁出现血管痉挛以及冷水试验后视野恶化表明，血管痉挛是不同潜在现象的一种表现。我们的结果表明，对于有眼血管痉挛的患者，用钙拮抗剂治疗可使他们的视野缺损明显好转。
