Kumar N, Jain S, Maheshwari M C
J Assoc Physicians India. 1989 May;37(5):315-7.
Forty patients of acute stroke of less than 48 hours duration above the age of 40 years were studied. All patients were evaluated as per the evaluation scoring system at the time of admission within 24 hours and 7 days after admission to hospital. 25 patients were given dexamethasone and 15 patients who were not given dexamethasone were matched for age, sex, underlying diseases and clinical condition as per the evaluation scoring. The mean evaluation score in study group showed significant improvement at 7 days (p less than 0.05) as compared to control group. There was no significant difference in mortality between the study and control group, being 36% and 33% respectively. Functional status also remained identical in the two groups at the time of discharge. There was also no significant difference in the outcome of patients of intracerebral haemorrhage vs. cerebral infarction whether treated with dexamethasone or not.
对40名年龄在40岁以上、病程少于48小时的急性中风患者进行了研究。所有患者在入院后24小时内及入院7天时，均按照评估评分系统进行评估。25名患者接受了地塞米松治疗，另外15名未接受地塞米松治疗的患者，根据评估评分在年龄、性别、基础疾病和临床状况方面进行了匹配。与对照组相比，研究组在7天时的平均评估评分有显著改善（p小于0.05）。研究组和对照组的死亡率分别为36%和33%，无显著差异。两组在出院时的功能状态也相同。脑出血与脑梗死患者无论是否接受地塞米松治疗，其结果也无显著差异。
