Antonelli Raíssa Quaiatti, Moreira Marcos Mello, Martins Luiz Claudio, Negro Maíra Soliani Del, Baldasso Tiago Antonio, Tincani Alfio José
Universidade Estadual de Campinas, Campinas, SP, Brazil.
Braz J Cardiovasc Surg. 2015 Nov-Dec;30(6):668-72. doi: 10.5935/1678-9741.20150089.
Mechanical ventilation is frequently necessary, in which case the use of an endotracheal tube is mandatory. The tube has an inflatable balloon in its distal extremity, whose aim is, among other functions, an efficient arterialization. However, serious injuries in the place of contact of the balloon with the trachea can be frequent. Some studies point out that balloons with permanent pressure may reduce this complication. Nevertheless, air scape, expressed by the inspiratory (IV) and expiratory volume (EV) variation (Δ IV-EV), may occur, possibly leading to hypoxemia. Thus, the goal of this study was to verify the efficiency of a modified endotracheal tube on arterializations compared to the traditional endotracheal tube.
The modified endotracheal tube presents intermittent insufflation, with three drillings in the internal region of the cuff, allowing for insufflation in the inspiratory phase of the mechanical ventilation. Three animals were used for the control group, with a cuff pressure of 30 cmH2O, and seven pigs had the modified endotracheal tube. Each animal was kept under mechanical ventilation (FIO2=0.21) for 6 hours. Arterial and venous gases were measured every three hours (T0; T3; T6).
The gases confirmed the lack of hypoxia between the Groups, with a difference in the ΔIV-EV at T0 (P=0.0486).
In this study, the lack of hypoxia showed the efficiency of the modified endotracheal tube. However, new studies are necessary, particularly in diseased lungs, in order to evaluate the real efficiency of the mentioned device on the pulmonary gas exchange.
机械通气常常是必要的,在这种情况下必须使用气管内导管。该导管在其远端有一个可充气的气囊,其目的之一是实现有效的动脉化。然而,气囊与气管接触部位频繁出现严重损伤。一些研究指出,具有恒定压力的气囊可能会减少这种并发症。尽管如此,可能会出现以吸气量(IV)和呼气量(EV)变化(ΔIV-EV)表示的漏气,这可能导致低氧血症。因此,本研究的目的是验证改良气管内导管与传统气管内导管相比在动脉化方面的效率。
改良气管内导管具有间歇性充气功能,在套囊内部区域有三个钻孔,可在机械通气的吸气阶段进行充气。对照组使用三只动物,套囊压力为30 cmH2O,七只猪使用改良气管内导管。每只动物在机械通气(FIO2=0.21)下保持6小时。每三小时(T0;T3;T6)测量动脉和静脉血气。
血气结果证实两组之间不存在缺氧情况,T0时ΔIV-EV存在差异(P=0.0486)。
在本研究中,无缺氧情况表明改良气管内导管是有效的。然而,需要进行新的研究,特别是在患病肺部,以评估上述装置在肺气体交换方面的实际效率。