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腹膜透析导管置入后的结局。

Outcomes after peritoneal dialysis catheter placement.

作者信息

Carpenter Jennifer L, Fallon Sara C, Swartz Sarah J, Minifee Paul K, Cass Darrell L, Nuchtern Jed G, Pimpalwar Ashwin P, Brandt Mary L

机构信息

Division of Pediatric Surgery, Department of Surgery, Texas Children's Hospital, Houston, TX; Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX.

Renal Service, Department of Pediatric Medicine, Texas Children's Hospital, Houston, TX.

出版信息

J Pediatr Surg. 2016 May;51(5):730-3. doi: 10.1016/j.jpedsurg.2016.02.011. Epub 2016 Feb 11.

Abstract

BACKGROUND

The purpose of this study was to review surgical outcomes after elective placement of peritoneal dialysis (PD) catheters in children with end-stage renal disease.

METHODS

Children with PD catheters placed between February 2002 and July 2014 were retrospectively reviewed. Outcomes were catheter life, late (>30days post-op) complications (catheter malfunction, catheter malposition, infection), and re-operation rates. Comparison groups included laparoscopic versus open placement, age<2, and weight<10kg. Univariate and multivariate analysis were performed.

RESULTS

One hundred sixteen patients had 173 catheters placed (122 open, 51 laparoscopic) with an average patient age of 9.7±6.3years. Mean catheter life was similar in the laparoscopic and open groups (581±539days versus 574±487days, p=0.938). The late complication rate was higher for open procedures (57% versus 37%, p=0.013). Children age<2 or weight<10kg had higher re-operation rates (64% versus 42%, p=0.014 and 73% versus 40%, p=0.001, respectively). Adjusted for age and weight, open technique remained a risk factor for late complications (OR 2.44, 95% CI 1.20-4.95) but not re-operation.

DISCUSSION

Laparoscopic placement appears to reduce the rate of late complications in children who require PD dialysis catheters. Children <2years age or <10kg remain at risk for complications regardless of technique.

摘要

背景

本研究的目的是回顾终末期肾病儿童择期置入腹膜透析(PD)导管后的手术结果。

方法

对2002年2月至2014年7月期间置入PD导管的儿童进行回顾性研究。观察指标包括导管使用寿命、晚期(术后>30天)并发症(导管功能障碍、导管位置异常、感染)及再次手术率。比较组包括腹腔镜置入与开放置入、年龄<2岁以及体重<10kg的情况。进行单因素和多因素分析。

结果

116例患者共置入173根导管(122根开放置入,51根腹腔镜置入),患者平均年龄为9.7±6.3岁。腹腔镜组和开放组的平均导管使用寿命相似(581±539天对574±487天,p = 0.938)。开放手术的晚期并发症发生率更高(57%对37%,p = 0.013)。年龄<2岁或体重<10kg的儿童再次手术率更高(分别为64%对42%,p = 0.014;73%对40%,p = 0.001)。校正年龄和体重后,开放技术仍是晚期并发症的危险因素(OR 2.44,95%CI 1.20 - 4.95),但不是再次手术的危险因素。

讨论

对于需要PD透析导管的儿童,腹腔镜置入似乎可降低晚期并发症的发生率。无论采用何种技术,年龄<2岁或体重<10kg的儿童仍有发生并发症的风险。

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