John Deepa Regina, Suthar Pokhraj P
Department of Radiology, Medical College and SSG Hospital, Vadodara, India.
Pol J Radiol. 2016 Feb 8;81:42-5. doi: 10.12659/PJR.896104. eCollection 2016.
Idiopathic hypoparathyroidism is an extremely rare endocrinal disorder with a prevalence of 37 per 100,000. Herein we presented a case of a 30-year-old male who came with symptoms of muscle weakness, carpopedal spasms and limitation of movement which gradually progressed over 8 years.
A 30-year-old male patient presented in an outpatient department of a tertiary care centre with a complaint of severe pain in both hip joints. He had generalized muscle weakness, facial discomfort, recurrent episodes of carpopedal spasms and crampy abdominal pains. On clinical examination, the patient had Chvostek sign and Trousseau sign. Biochemical tests revealed hypocalcemia, hyperphosphatemia and hypomagnesemia with low plasma parathyroid hormone level. X-ray of the pelvis and spine revealed spondylarthropathic changes of long-standing hypoparathyroidism. Computed Tomography of the brain revealed bilateral basal ganglia calcifications. The patient was treated with intravenous calcium gluconate, magnesium and oral vitamin D3. On follow-up the patient showed improvement of muscle weakness and carpopedal spasm with near-normal biochemical parameters. However, there was no improvement in symptoms related to spondyloarthropathy.
Idiopathic hypoparathyroidism is a rare endocrine disorder with clinic and biochemical features of hypocalcemia. Long- standing hypoparathyroidism can cause spondyloarthropathic changes closely resembling ankylosing spondylitis and DISH. Skeletal changes of long-standing hypoparathyroidism are irreversible. If left untreated, life-threatening complications like cardiac arrhythmias and broncholaryngospasm may occur.
特发性甲状旁腺功能减退症是一种极其罕见的内分泌疾病，患病率为每10万人中有37例。在此，我们报告一例30岁男性患者，其出现肌肉无力、手足痉挛和运动受限症状，这些症状在8年里逐渐进展。
一名30岁男性患者到一家三级护理中心门诊就诊，主诉双侧髋关节剧痛。他有全身肌肉无力、面部不适、反复出现手足痉挛和痉挛性腹痛。临床检查时，患者有Chvostek征和Trousseau征。生化检查显示低钙血症、高磷血症和低镁血症，血浆甲状旁腺激素水平低。骨盆和脊柱X线检查显示长期甲状旁腺功能减退症的脊椎关节病改变。脑部计算机断层扫描显示双侧基底节钙化。患者接受了静脉注射葡萄糖酸钙、镁和口服维生素D3治疗。随访时，患者肌肉无力和手足痉挛症状改善，生化指标接近正常。然而，与脊椎关节病相关的症状没有改善。
特发性甲状旁腺功能减退症是一种罕见的内分泌疾病，具有低钙血症的临床和生化特征。长期甲状旁腺功能减退症可导致与强直性脊柱炎和弥漫性特发性骨肥厚非常相似的脊椎关节病改变。长期甲状旁腺功能减退症的骨骼改变是不可逆的。如果不治疗，可能会发生危及生命的并发症，如心律失常和支气管喉痉挛。
