Türkoğlu Sefa, Toprak Uğur, Aydoğan Çiğdem, Kutlu Özgür Timuçin
Department of Radiology, Denizli State Hospital, Denizli, Turkey.
Department of Radiology, Osmangazi University Medical Faculty, Eskişehir, Turkey.
Turk J Phys Med Rehabil. 2020 Mar 3;66(1):92-95. doi: 10.5606/tftrd.2020.2944. eCollection 2020 Mar.
Hypoparathyroidism is an endocrinopathy that can develop idiopathically, as well as due to reasons associated with genetics, autoimmunity, surgery and radiotherapy. It usually presents with neuromuscular signs and symptoms, including enthesopathy caused by calcification of the ligament and enthesis sites, soft tissue calcification, hypertension, cataract and extrapyramidal findings due to basal ganglia calcification. Hypoparathyroidism-associated spondyloarthropathy (SpA) is a rarely seen clinical entity. Hypoparathyroidism-associated SpA differs from other inflammatory SpAs in that the results for human leukocyte antigen B27 and inflammatory markers are negative and bone density is normal. The symptoms are relieved by calcium and vitamin D, rather than anti-inflammatory drugs. Due to this difference in treatment modalities, the diagnosis of this type of SpA is important. This article presents the case report of a 52-year-old female patient with iatrogenic hypoparathyroidism accompanied by asymptomatic hypocalcemia and SpA clinic.
甲状旁腺功能减退是一种内分泌病，可特发性发生，也可由与遗传、自身免疫、手术及放疗相关的原因引起。它通常表现为神经肌肉体征和症状，包括韧带和附着点钙化所致的附着点病、软组织钙化、高血压、白内障以及基底节钙化引起的锥体外系表现。甲状旁腺功能减退相关的脊柱关节炎（SpA）是一种罕见的临床实体。甲状旁腺功能减退相关的SpA与其他炎性SpA不同，其人类白细胞抗原B27及炎性标志物结果为阴性，且骨密度正常。症状通过补充钙和维生素D缓解，而非使用抗炎药物。由于治疗方式存在这种差异，此类SpA的诊断很重要。本文介绍了一名52岁女性患者的病例报告，该患者患有医源性甲状旁腺功能减退，伴有无症状性低钙血症及SpA临床症状。
