Couture Danielle Chung, Chung Myung Kyu, Shinnick Phillip, Curzon Jonathan, McClure Mark J, LaRiccia Patrick J
Perelman School of Medicine at the University of Pennsylvania, Philadelphia (Dr Couture), United States.
Cooper Medical School of Rowan University, Camden, New Jersey; Chung Institute of Integrative Medicine; Won Sook Chung Foundation, Moorestown, New Jersey (Dr Chung), United States.
Glob Adv Health Med. 2016 Jan;5(1):117-21. doi: 10.7453/gahmj.2015.091. Epub 2016 Jan 1.
Pediatric obsessive-compulsive disorder (OCD) is prevalent in 1% to 2% of the population. Emerging studies have correlated non-celiac gluten sensitivity with psychiatric conditions such as schizophrenia, depression, mania, and anxiety. This case study is the first reported case of OCD associated with non-celiac gluten sensitivity. The objectives of this case report are to (1) identify gluten sensitivity as a possible contributing factor to OCD in some patients; and (2) point out the possible benefit of an integrative medicine approach to the management of OCD in a patient with suboptimal benefit from a standard treatment regime. A 7-year-old male treated at a multi-physician integrative medicine practice in the United States had marked reduction of OCD symptoms and anxiety along with marked improvement of social behavior and school work after treatment consisting of gluten avoidance and other integrative medicine modalities. The patient's rapid response without side effects behooves the medical research community to further investigate the association of non-celiac gluten sensitivity and pediatric OCD.
小儿强迫症（OCD）在1%至2%的人群中普遍存在。新兴研究已将非乳糜泻性麸质敏感与精神疾病如精神分裂症、抑郁症、躁狂症和焦虑症联系起来。本病例研究是首例报告的与非乳糜泻性麸质敏感相关的强迫症病例。本病例报告的目的是：（1）确定麸质敏感是某些患者强迫症的一个可能促成因素；（2）指出对于一名从标准治疗方案中获益不佳的强迫症患者，采用综合医学方法进行管理可能带来的益处。一名在美国一家多位医生综合医学诊所接受治疗的7岁男性，在采用避免麸质及其他综合医学方法治疗后，强迫症症状和焦虑明显减轻，社交行为和学业成绩也显著改善。该患者迅速起效且无副作用，这促使医学研究界进一步研究非乳糜泻性麸质敏感与小儿强迫症之间的关联。
