Shahlaee Abtin, Hong Bryan K, Ho Allen C
Retina Service of Wills Eye Hospital, Mid Atlantic Retina, Philadelphia, Pennsylvania.
Retin Cases Brief Rep. 2017;11(1):90-93. doi: 10.1097/ICB.0000000000000297.
Optical coherence tomography angiography (OCTA) is a novel technology that uses motion contrast instead of dye to generate angiographic images. Using several modalities of OCTA, the authors describe and compare changes observed in branch retinal vein occlusion.
A case series of three patients with OCTA imaging.
Despite presenting at different time frames, the authors found common imaging findings consisting of vascular hypoperfusion, increased tortuosity, and telangiectasia in all their cases. Furthermore, macular edema and intraretinal fluid were noted on the en-face angiograms. The extent of vascular and structural alterations could clearly be delineated in superficial and deep retinal networks. However, fine capillary alterations were better appreciated on smaller-size scans.
With the ability to noninvasively visualize vascular flow, OCTA could serve as a new diagnostic tool for current ophthalmic research and clinical practice. Such findings can help supplement other imaging modalities in establishing a diagnosis and monitoring disease progression over time. This would potentially be useful in regard to ischemic processes such as branch retinal vein occlusion and diseases affecting different layers of the retinal vasculature.
光学相干断层扫描血管造影(OCTA)是一种利用运动对比而非染料来生成血管造影图像的新技术。作者使用多种OCTA模式,描述并比较了视网膜分支静脉阻塞中观察到的变化。
对3例患者进行OCTA成像的病例系列研究。
尽管患者就诊时间不同,但作者发现所有病例的共同成像表现包括血管灌注不足、迂曲增加和毛细血管扩张。此外,在正面血管造影图上还发现了黄斑水肿和视网膜内液。血管和结构改变的程度在视网膜浅、深层网络中可清晰描绘。然而,在较小尺寸扫描中能更好地观察到微小毛细血管改变。
由于能够无创地可视化血管血流,OCTA可作为当前眼科研究和临床实践的一种新诊断工具。这些发现有助于在疾病诊断和长期监测疾病进展过程中补充其他成像模式。这对于诸如视网膜分支静脉阻塞等缺血性疾病以及影响视网膜血管不同层次的疾病可能具有潜在用途。