Li Xiaomin, Wang Jing, Zhang Qinghe, Li Hongmei
Se Pu. 2015 Nov;33(11):1147-54. doi: 10.3724/sp.j.1123.2015.06027.
Phthalate esters are most widely used as plasticizers which have toxicity and carcinogenicity. Phthalate esters are found as contaminants in many food products and they are a branch of compounds, homologues and isomers, which present similar structures and properties. And the residue contents vary a lot in different matrices. Efficient sample pretreatment, highly selective separation mode, sensitive detection methods as well as reducing background interference are challenges for their determination in complex samples. In this paper, some sample pretreatment methods such as liquid-liquid extraction, liquid-liquid micro-extraction, solid phase extraction, solid phase micro-extraction, matrix solid-phase extraction and other traditional and new types of extraction and purification technology applied in the food samples are reviewed. The characteristics of analytical methods including gas chromatography, liquid chromatography, tandem mass spectrometry, high resolution mass spectrometry, enzyme-linked immunoassay, and ion mobility spectrometry are also discussed.
邻苯二甲酸酯作为具有毒性和致癌性的增塑剂被广泛使用。在许多食品中都发现邻苯二甲酸酯是污染物，它们是一类化合物、同系物和异构体，具有相似的结构和性质。并且在不同基质中其残留量差异很大。高效的样品前处理、高选择性的分离模式、灵敏的检测方法以及减少背景干扰是在复杂样品中对其进行测定面临的挑战。本文综述了一些应用于食品样品的样品前处理方法，如液液萃取、液液微萃取、固相萃取、固相微萃取、基质固相萃取以及其他传统和新型的萃取与净化技术。还讨论了包括气相色谱、液相色谱、串联质谱、高分辨率质谱、酶联免疫分析和离子迁移谱等分析方法的特点。
