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Upstream therapeutic strategies of Valsartan and Fluvastatin on Hypertensive patients with non-permanent Atrial Fibrillation (VF-HT-AF): study protocol for a randomized controlled trial.缬沙坦和氟伐他汀对非永久性心房颤动高血压患者(VF-HT-AF)的上游治疗策略:一项随机对照试验的研究方案
Trials. 2015 Aug 7;16:336. doi: 10.1186/s13063-015-0836-5.
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J Am Soc Hypertens. 2015 Jun;9(6):453-98. doi: 10.1016/j.jash.2015.03.002. Epub 2015 Mar 31.
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Beneficial effects of losartan for prevention of paroxysmal atrial fibrillation in patients with sick sinus syndrome: analysis with memory function of pacemaker.氯沙坦对病态窦房结综合征患者预防阵发性心房颤动的有益作用:基于起搏器记忆功能的分析
Heart Vessels. 2016 Mar;31(3):402-7. doi: 10.1007/s00380-015-0627-7. Epub 2015 Mar 19.
6
Initial reduction of oxidative stress by angiotensin receptor blocker contributes long term outcomes after percutaneous coronary intervention.血管紧张素受体阻滞剂对氧化应激的初始降低作用有助于经皮冠状动脉介入治疗后的长期预后。
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Diagnosis, treatment, and prevention of gout.痛风的诊断、治疗与预防。
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Different angiotensin receptor blockers and incidence of diabetes: a nationwide population-based cohort study.不同血管紧张素受体阻滞剂与糖尿病发病率:一项基于全国人群的队列研究。
Cardiovasc Diabetol. 2014 May 14;13:91. doi: 10.1186/1475-2840-13-91.

ARB类药物的不同治疗选择。该选用哪一种?何时使用?为何这样用?

The Different Therapeutic Choices with ARBs. Which One to Give? When? Why?

作者信息

Dézsi Csaba András

机构信息

Department of Cardiology, Petz Aladár County Teaching Hospital, Gyor, Hungary.

出版信息

Am J Cardiovasc Drugs. 2016 Aug;16(4):255-266. doi: 10.1007/s40256-016-0165-4.

DOI:10.1007/s40256-016-0165-4
PMID:26940560
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4947116/
Abstract

The renin-angiotensin-aldosterone system plays an important role in the pathophysiology of hypertension and is closely related with cardio- and cerebrovascular events and chronic kidney diseases. Each angiotensin receptor blocker (ARB) is important in the treatment of hypertension, according to the results of recent years. This is a practical review of the available evidence on the different benefits of ARBs beyond their blood pressure-lowering effect, with an emphasis on the differences found between the particular compounds and the therapeutic implications of the findings, with specific reference to the co-morbidities.

摘要

肾素-血管紧张素-醛固酮系统在高血压的病理生理学中起重要作用,并且与心脑血管事件及慢性肾脏疾病密切相关。根据近年来的研究结果,每种血管紧张素受体阻滞剂(ARB)在高血压治疗中都很重要。本文对ARB除降压作用外的不同益处的现有证据进行了实用综述,重点阐述了特定化合物之间的差异以及这些发现的治疗意义,并特别提及了合并症。