Jackler R K
Department of Otolaryngology-Head and Neck Surgery, University of California School of Medicine, San Francisco.
Otolaryngol Clin North Am. 1989 Oct;22(5):883-96.
The majority of cholesteatomas assume typical growth patterns that are dictated by their site of origin and related anatomic structures. These routes of penetration tend to develop along vestigial planes that were created during the embryogenesis of the middle ear and mastoid. Knowledge of the relevant surgical anatomy allows the surgeon to recognize and remedy pathologic changes and avoid complications.