两株属于欧美S家族的广泛耐药结核分枝杆菌的基因组序列草图
Draft Genome Sequences of Two Extensively Drug-Resistant Strains of Mycobacterium tuberculosis Belonging to the Euro-American S Lineage.
作者信息
Malinga Lesibana A, Abeel Thomas, Desjardins Christopher A, Dlamini Talent C, Cassell Gail, Chapman Sinéad B, Birren Bruce W, Earl Ashlee M, van der Walt Martie
机构信息
South African Medical Research Council TB Platform, Pretoria, Gauteng, South Africa Department of Internal Medicine, University of Pretoria, Pretoria, Gauteng, South Africa
Broad Institute, Cambridge, Massachusetts, USA Delft Bioinformatics Laboratory, Delft University of Technology, Delft, The Netherlands.
出版信息
Genome Announc. 2016 Mar 3;4(2):e01771-15. doi: 10.1128/genomeA.01771-15.
Abstract
We report the whole-genome sequencing of two extensively drug-resistant tuberculosis strains belonging to the Euro-American S lineage. The RSA 114 strain showed single-nucleotide polymorphisms predicted to have drug efflux activity.
摘要
我们报告了两株属于欧美S谱系的广泛耐药结核菌株的全基因组测序结果。RSA 114菌株显示出预测具有药物外排活性的单核苷酸多态性。
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