Dobrilla G, Valentini M, Bonoldi M C, Piazzi L
Division of Gastroenterology, Regional General Hospital, Bolzano, Italy.
Scand J Gastroenterol Suppl. 1989;167:65-7. doi: 10.3109/00365528909091315.
Forty outpatients with endoscopically confirmed duodenal ulcers were entered in a double blind trial. They were randomly allocated to octatropine-methyl-bromide and sulglycotide salt (GVP) or placebo. The results show that the combination of the two drugs is less efficacious than the two constituent substances taken separately, is not more efficacious than placebo in ulcer healing, and is ineffective with regard to ulcer pain.
40例经内镜确诊为十二指肠溃疡的门诊患者进入一项双盲试验。他们被随机分配接受溴甲辛托品和硫糖铝盐（GVP）或安慰剂治疗。结果表明，两种药物联合使用的疗效低于单独使用两种成分药物，在溃疡愈合方面并不比安慰剂更有效，且对溃疡疼痛无效。
