Nakayama Yusuke, Kato Yuichiro, Okubo Satoshi, Takahashi Daigoro, Okada Rei, Nishida Yasunori, Kitaguchi Kazuhiko, Gotohda Naoto, Takahashi Shinichiro, Konishi Masaru
Division of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, 277-8577, Japan.
Surg Case Rep. 2015 Dec;1(1):9. doi: 10.1186/s40792-014-0007-z. Epub 2015 Jan 30.
A 71-year-old woman was referred to our institution for further investigation of epigastric pain. The patient had been detected to have a multilocular cyst in the medial segment of the liver measuring 69 mm in diameter at another hospital 2 years ago, and the diameter of the cyst had increased to 90 mm. Although the cyst had gradually increased in size, there was no evidence of mural nodules. As we were concerned about the malignant potential of the lesion, a left hepatic segmentectomy was performed. Pathologically, the cyst was lined by columnar and cuboidal epithelium with low-grade atypia. The epithelium covered an ovarian-like stroma, and the diagnosis was mucinous cystic neoplasm of the liver (MCN-L) with low-grade intraepithelial neoplasia. MCN-L is a rare disease and its characteristics are still poorly understood. MCN-L occurs at a lower frequency as compared to the counterpart of MCN of the pancreas, further investigations are necessary to clarify the biological malignancy of MCN-L.
一名71岁女性因上腹部疼痛被转诊至我院作进一步检查。该患者两年前在另一家医院被检测出肝脏内侧段有一个直径69毫米的多房性囊肿,囊肿直径现已增至90毫米。尽管囊肿大小逐渐增大,但未发现壁结节。由于我们担心该病变的恶性潜能,遂行左肝段切除术。病理检查显示,囊肿内衬柱状和立方上皮,伴低度异型性。上皮覆盖类似卵巢的间质,诊断为肝脏黏液性囊性肿瘤(MCN-L)伴低度上皮内瘤变。MCN-L是一种罕见疾病,其特征仍知之甚少。与胰腺黏液性囊性肿瘤相比,MCN-L的发病率较低,需要进一步研究以阐明MCN-L的生物学恶性程度。