Ezaki Sayuri, Tomimaru Yoshito, Noguchi Kozo, Nagase Hirotsugu, Ogino Takayuki, Hirota Masashi, Oshima Kazuki, Tanida Tsukasa, Noura Shingo, Imamura Hiroshi, Iwazawa Takashi, Akagi Kenzo, Dono Keizo
Dept. of Surgery, Toyonaka Municipal Hospital.
Gan To Kagaku Ryoho. 2018 Dec;45(13):2303-2305.
A 55 -year-old woman presented at our hospital in 2017. In 2014, a large cyst had been detected in her liver by ultrasonography, and she was followed up at a clinic. Abdominal computed tomography(CT)revealed a large multilocular cystic tumor measuring 12 cm in diameter in the left lobe of the liver. Although no solid component was identified in the tumor, the cystic tumor was increasing in size, and the serum level of CA19-9 was elevated. Under a preoperative diagnosis of mucinous cystic neoplasm(MCN)of the liver, we performed extended left liver lobectomy. There were no postoperative complications. Histopathological examination of the resected specimen revealed low-grade intraepithelial neoplasia, and the epithelium covered an ovarian-type stroma. The ovarian-type stromal cells were immunoreactive for estrogen receptor and progesterone receptor. The definitive diagnosis of the tumor was MCN of the liver with low-grade intraepithelial neoplasia. Eight months after the surgery, the patient remains alive without any recurrence.
一名55岁女性于2017年前来我院就诊。2014年，超声检查发现其肝脏有一个大囊肿，她在一家诊所接受随访。腹部计算机断层扫描（CT）显示肝脏左叶有一个直径12厘米的巨大多房性囊性肿瘤。尽管肿瘤内未发现实性成分，但囊性肿瘤大小在增加，且血清CA19-9水平升高。在术前诊断为肝脏黏液性囊性肿瘤（MCN）的情况下，我们进行了扩大左肝叶切除术。术后无并发症。对切除标本进行组织病理学检查显示为低级别上皮内瘤变，上皮覆盖卵巢型间质。卵巢型间质细胞对雌激素受体和孕激素受体呈免疫反应阳性。该肿瘤的最终诊断为肝脏MCN伴低级别上皮内瘤变。手术后八个月，患者仍存活，无任何复发迹象。
