Kesmodel Ulrik S, Petersen Gitte L, Henriksen Tine B, Strandberg-Larsen Katrine
Department of Obstetrics and Gynecology, Herlev University Hospital, Herlev, Denmark.
Department for Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Acta Obstet Gynecol Scand. 2016 Jul;95(7):803-10. doi: 10.1111/aogs.12890. Epub 2016 Mar 31.
In 1999, Danish health authorities modified their recommendation to pregnant women, condoning some alcohol intake. In 2007, the recommendation was changed to one of alcohol abstention. We aimed to assess changes in average alcohol intake (drinks/week) and alcohol binge drinking in early pregnancy from 1998 to 2013 in relation to the changes in official recommendations in 1999 (condoning some intake) and 2007 (abstention).
All Danish-speaking pregnant women attending routine antenatal care at the Department of Obstetrics and Gynecology, Aarhus University Hospital, Denmark, between September 1998 and June 2013 were invited to participate. During the study period, 68 395 pregnant women filled in a self-administered questionnaire at gestational week 11 (median). From 1998, questions on binge drinking included data on the number of binge episodes (≥5 drinks on a single occasion), and the timing (gestational week) of these episodes. Additional questions on binge drinking defined as ≥3 drinks on a single occasion were asked separately from 2000. A question assessed the average number of alcohol-containing drinks per week the woman consumed currently at the time of filling in the questionnaire.
From 1998 to 2013 the proportion of women reporting no alcohol intake increased from 31.2 to 83.3% (p < 0.001), the main decline occurring between 1998 and 2007. The proportion of binge drinkers decreased (p < 0.001) but remained more stable across the period.
The decline in the proportion of pregnant women consuming alcohol occurred independently of official recommendations. Increasing national and international awareness may partly explain the changes.
1999年，丹麦卫生当局修改了对孕妇的建议，允许孕妇摄入一定量酒精。2007年，该建议改为完全戒酒。我们旨在评估1998年至2013年孕早期孕妇平均酒精摄入量（每周饮酒量）和暴饮情况的变化，以及这些变化与1999年（允许一定量摄入）和2007年（戒酒）官方建议变化之间的关系。
邀请1998年9月至2013年6月期间在丹麦奥胡斯大学医院妇产科接受常规产前检查的所有丹麦语孕妇参与研究。在研究期间，68395名孕妇在妊娠第11周（中位数）填写了一份自填问卷。从1998年起，关于暴饮的问题包括暴饮次数（单次饮酒≥5杯）的数据以及这些暴饮事件发生的时间（孕周）。从2000年起，单独询问了关于单次饮酒≥3杯的暴饮情况的其他问题。一个问题评估了女性在填写问卷时当前每周饮用含酒精饮料的平均数量。
从1998年到2013年，报告不饮酒的女性比例从31.2%上升到83.3%（p<0.001），主要下降发生在1998年至2007年之间。暴饮者的比例下降（p<0.001），但在整个时期内保持相对稳定。
孕妇饮酒比例的下降与官方建议无关。国家和国际意识的提高可能部分解释了这些变化。
