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孕期机器人辅助肾部分切除术:病例报告及特殊考量

Robotic Partial Nephrectomy During Pregnancy: Case Report and Special Considerations.

作者信息

Ramirez Daniel, Maurice Matthew J, Seager Catherine, Haber Georges-Pascal

机构信息

Cleveland Clinic, Glickman Urological and Kidney Institute, Cleveland, OH.

Cleveland Clinic, Glickman Urological and Kidney Institute, Cleveland, OH.

出版信息

Urology. 2016 Jun;92:1-5. doi: 10.1016/j.urology.2015.11.037. Epub 2016 Mar 2.

Abstract

OBJECTIVE

To report a case of robotic partial nephrectomy (RPN) during pregnancy and review the existing literature on the topic.

METHODS

A 35-year-old asymptomatic pregnant woman at 20 weeks gestation was found to have a large mass in the right kidney during routine anatomic ultrasound for fetal assessment. Magnetic resonance imaging demonstrated a 7.5 cm right upper-pole solid-enhancing renal mass, concerning for malignancy, without evidence of local extension or metastases. Ultimately, after shared decision-making between the patient and her physicians, the patient elected to proceed with RPN. A multidisciplinary approach was undertaken perioperatively. Notably, coordination between high-risk maternal fetal medicine, obstetrics, anesthesia, and urology were paramount to this endeavor.

RESULTS

The patient was seen and assessed by obstetrics and maternal fetal medicine preoperatively, and fetal heart tones were monitored immediately before and after surgery and every day of her hospitalization. Total operating time was 253 minutes with an estimated blood loss of 120 cc. Warm ischemia time was 36 minutes, and 70% of normal renal parenchyma was preserved. The patient's creatinine peaked at 0.81 mg/dL, and her hemoglobin nadir reached 9.6 g/dL. She was discharged on postoperative day 6 in excellent condition. Final pathology demonstrated a 6.6 cm chromophobe renal cell carcinoma with negative margins.

CONCLUSION

RPN during pregnancy is feasible but requires perioperative planning, multidisciplinary coordination, and careful operative decision-making to ensure optimal safety of mother and fetus. Herein, we report the first described case of RPN for renal neoplasm during pregnancy.

摘要

目的

报告一例孕期机器人辅助部分肾切除术(RPN)病例,并回顾该主题的现有文献。

方法

一名35岁、孕20周的无症状孕妇在进行常规胎儿解剖超声检查时发现右肾有一个大肿块。磁共振成像显示右肾上极有一个7.5厘米的实性强化肾肿块,怀疑为恶性肿瘤,无局部扩展或转移的证据。最终,在患者与其医生共同决策后,患者选择进行RPN。围手术期采用多学科方法。值得注意的是,高危母胎医学、产科、麻醉科和泌尿外科之间的协调对这一努力至关重要。

结果

术前由产科和母胎医学对患者进行检查和评估,手术前后及住院期间每天监测胎心音。总手术时间为253分钟,估计失血量为120毫升。热缺血时间为36分钟,保留了70%的正常肾实质。患者的肌酐峰值为0.81毫克/分升,血红蛋白最低点达到9.6克/分升。她在术后第6天状况良好出院。最终病理显示为一个6.6厘米的嫌色肾细胞癌,切缘阴性。

结论

孕期RPN是可行的,但需要围手术期规划、多学科协调和谨慎的手术决策,以确保母亲和胎儿的最佳安全。在此,我们报告了首例孕期因肾肿瘤行RPN的病例。

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