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一位 27 岁的初产妇,在 30 孕周时通过机器人辅助后腹腔镜部分肾切除术切除右侧肾细胞癌。

A 27-Year-Old Primigravida with a Right Renal Cell Carcinoma Removed at 30 Weeks of Gestation by Robot-Assisted Retroperitoneoscopic Partial Nephrectomy.

机构信息

Department of Urology, Darmstadt Hospital, Hessen, Germany.

Department of Urology, Hochtaunus-Hospitals, Bad Homburg vor der Höhe, Germany.

出版信息

Am J Case Rep. 2021 Apr 18;22:e927164. doi: 10.12659/AJCR.927164.

Abstract

BACKGROUND Large renal tumors during pregnancy are rare findings (0.07-0.1%). Current guidelines recommend surgical removal. This surgery should be carefully planned in an interdisciplinary team and involves special risks for mother and fetus. This report describes a case of a 27-year-old primigravida woman with a right renal cell carcinoma involving the lower pole of the kidney, which was removed at 30 weeks of gestation by robot-assisted retroperitoneoscopic partial nephrectomy (RARPN). CASE REPORT The patient was referred by the treating obstetrician with a newly diagnosed right lower pole renal mass of 6×4 cm in greatest diameter extending deeply into the parenchyma. No metastasis or enlarged lymph nodes were described in subsequent magnetic resonance tomography. Clinical and laboratory examinations documented a healthy mother and fetus. A right-sided RARPN was advised and planned by an interdisciplinary team of treating physicians (gynecologists, oncologists, and urologists). The surgery was conducted under general anesthesia with an obstetrician on stand-by. Surgery was performed without any complications (operation time 95 min, renal-ischemia time 15 min, and negligible blood loss) and histopathology confirmed the diagnosis of a chromophobe renal cell carcinoma. Further follow-up consultations showed regular wound healing and normal progression of pregnancy, and the patient gave birth to a healthy child at term. Follow-up examinations of the patient were uneventful. CONCLUSIONS This case shows that RARPN can be a safe and effective surgical procedure for partial nephrectomy during pregnancy, where surgery is performed in a specialist center and by an interdisciplinary experienced surgical team. It seems to offer advantages and better risk profile over the laparoscopic approach.

摘要

背景

怀孕期间出现大型肾脏肿瘤较为罕见(0.07-0.1%)。目前的指南建议进行手术切除。此类手术需要在多学科团队中精心规划,并且对母婴都存在特殊风险。本报告描述了一例 27 岁初产妇,右侧肾脏下极存在肾细胞癌,直径约 6×4cm,深入肾实质。随后的磁共振成像并未描述转移或淋巴结肿大。临床和实验室检查显示母亲和胎儿均健康。随后由妇产科医生、肿瘤学家和泌尿科医生组成的多学科治疗医师团队建议并计划实施右侧机器人辅助后腹腔镜下部分肾切除术(RARPN)。病例报告:患者由主治妇产科医生转诊,诊断为右侧下极肾肿块,最大直径 6×4cm,深入肾实质。随后的磁共振成像并未描述转移或淋巴结肿大。临床和实验室检查显示母亲和胎儿均健康。建议并计划实施右侧 RARPN。手术由多学科治疗医师团队(妇产科医生、肿瘤学家和泌尿科医生)在全身麻醉下进行,同时有一名产科医生待命。手术过程顺利,无任何并发症(手术时间 95 分钟,肾脏缺血时间 15 分钟,失血量可忽略不计),组织病理学检查证实为嫌色细胞肾细胞癌。进一步的随访咨询显示伤口愈合正常,妊娠进展正常,患者足月分娩一健康婴儿。患者的后续检查也未见异常。结论:本病例表明,对于在专家中心由经验丰富的多学科手术团队进行的妊娠期间部分肾切除术,RARPN 是一种安全有效的手术方法。与腹腔镜方法相比,它似乎具有优势和更好的风险特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b24/8063764/a43c22f851dd/amjcaserep-22-e927164-g001.jpg

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