Kabata Piotr, Schetz Daria, Waldman Wojciech, Wiergowsk Marek, Sein Anand Jacek
Przegl Lek. 2015;72(10):517-21.
During initial months of the year 2015 we observed the increase number of patients intoxicated with NPS in Poland. In our work we analysed the scale of this phenomenon in Pomeranian region.
Study was carried out on period from 1 January 2015 to 31 July 2015. Analysis was based on records derived from Electronic Poison Information Database developed and used on a daily basis on Pomeranian Centre of Toxicology (PCT), data obtained from Centre for Monitoring of Adverse Effects of Medicaments and Chemical Substances based in PCT and on information gathered from patients treated in Pomeranian Centre of Toxicology for NPS intoxication.
Our study has shown slow, continuous rise in the number of intoxications with NPS in analysed period. The most frequent cause of intoxication were synthetic compounds. 99 cases needed treatment in Clinical Toxicology Unit due to their severe state. The youngest exposed person was 13 y.o., while the oldest was 53 y.o. Mean age was 22.5 y.o. with median 20 years. Majority of intoxications were among males (80.54%). 61.53% of all patients came from Tricity agglomeration. Ethanol was the prevalent coingestant. The most commonly used substance was generic NPS (70.59% of cases), followed by unknowns psychoactive substance (16.29% of cases), herbal mixture (16.29% of cases) and dextrometorphan (5.88% of cases). The study did not find one drug name that would be prevalent over others, with the most frequent commercial name being "Mocarz", found in 4 cases. Most dangerous substances found in NPS were PMA, PMMA, 25C-NBOMe and 251-NBOMe. There were no deaths of patients treated in PCT because of acute intoxication with NPS.
在2015年的最初几个月里，我们观察到波兰新型精神活性物质（NPS）中毒患者数量有所增加。在我们的研究中，我们分析了波美拉尼亚地区这一现象的规模。
研究于2015年1月1日至2015年7月31日期间进行。分析基于从波美拉尼亚毒理学中心（PCT）日常开发和使用的电子毒物信息数据库中获取的记录、从基于PCT的药物和化学物质不良反应监测中心获得的数据，以及从在波美拉尼亚毒理学中心接受NPS中毒治疗的患者那里收集到的信息。
我们的研究表明，在分析期内，NPS中毒患者数量呈缓慢、持续上升趋势。中毒的最常见原因是合成化合物。99例患者因病情严重需要在临床毒理学科室接受治疗。最年轻的接触者为13岁，最年长者为53岁。平均年龄为22.5岁，中位数为20岁。大多数中毒患者为男性（80.54%）。所有患者中有61.53%来自三联城集聚区。乙醇是最常见的共同摄入物质。最常用的物质是普通NPS（占病例的70.59%），其次是未知精神活性物质（占病例的16.29%）、草药混合物（占病例的16.29%）和右美沙芬（占病例的5.88%）。该研究未发现一种药物名称比其他名称更普遍，最常见的商品名为“Mocarz”，有4例。在NPS中发现的最危险物质是PMA、PMMA、25C-NBOMe和251-NBOMe。在PCT接受治疗的患者中，没有因NPS急性中毒死亡的病例。
