Department of Urology, Sector Furore, Erasmus Medical Centre, Rotterdam, The Netherlands.
Department of Urology, Sector Furore, Erasmus Medical Centre, Rotterdam, The Netherlands.
J Urol. 2016 Aug;196(2):490-7. doi: 10.1016/j.juro.2016.02.2966. Epub 2016 Mar 3.
We developed a noninvasive method to diagnose bladder outlet obstruction. An ultrasound based decorrelation method was applied in male patients with lower urinary tract symptoms.
In 60 patients ultrasound data were acquired transperineally while they were voiding while sitting. Each patient also underwent a standard invasive pressure flow study.
High frequent sequential ultrasound images were successfully recorded during voiding in 45 patients. The decorrelation (decrease in correlation) between subsequent ultrasound images was higher in patients with bladder outlet obstruction than in unobstructed patients and healthy volunteers. ROC analysis resulted in an AUC of 0.96, 95% specificity and 88% sensitivity. A linear relationship was fitted to the decorrelation values as a function of the degree of obstruction represented by the bladder outlet obstruction index, measured in the separate pressure flow studies.
It is possible to noninvasively diagnose bladder outlet obstruction using the ultrasound decorrelation technique.
我们开发了一种非侵入性方法来诊断膀胱出口梗阻。在患有下尿路症状的男性患者中应用了基于超声的去相关方法。
在 60 名患者中，在他们坐著排尿时经会阴采集超声数据。每位患者还接受了标准的侵入性压力流研究。
在 45 名患者中成功记录了高频序贯超声图像。与未梗阻患者和健康志愿者相比，梗阻患者的后续超声图像之间的去相关（相关性降低）更高。ROC 分析得出 AUC 为 0.96，95%特异性和 88%敏感性。将去相关值拟合为线性关系，作为单独压力流研究中测量的膀胱出口梗阻指数的梗阻程度的函数。
使用超声去相关技术可以无创诊断膀胱出口梗阻。
