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机会成本与政策:加拿大曼尼托巴省血糖自我监测的使用情况评估

Opportunity Cost and Policy: A Utilization Review of Self-monitoring of Blood Glucose in Manitoba, Canada.

作者信息

Serwylo Olena, Friesen Kevin, Falk Jamie, Bugden Shawn

机构信息

Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada.

Faculty of Health Sciences, College of Pharmacy, University of Manitoba, Winnipeg, Manitoba, Canada.

出版信息

Clin Ther. 2016 Apr;38(4):929-35. doi: 10.1016/j.clinthera.2016.02.011. Epub 2016 Mar 2.

Abstract

PURPOSE

Recently, there has been a re-evaluation of the frequency, benefits, and costs associated with self-monitoring of blood glucose (SMBG). Based on little evidence of the benefit of frequent SMBG in patients with diabetes not using insulin, new guidelines and test strip limit policies have been suggested and implemented in various Canadian jurisdictions to promote a more selective practice of SMBG. The objective of this study was to assess the overall utilization and cost associated with test strips and lancets for SMBG in Manitoba from 2000 to 2013 as well as to explore the policy implications of the implementation of test strip quantity limits and its impact on overall and government costs.

METHODS

An analysis of prescription claims for blood glucose test strips (BGTSs) and lancets for all patients with diabetes in Manitoba from 2000 to 2013 was conducted. In each year, patients were stratified into 4 mutually exclusive hierarchical groups according to most intensive diabetes treatment. Test strip and lancet utilization and cost were assessed for each group in each year, and the potential cost savings associated with implementation of a BGTS limit policy was projected using autoregressive integrated moving average models.

FINDINGS

In the year 2000, 8 million test strips were dispensed in Manitoba, increasing by 170% to 21.7 million test strips in 2013. Insulin users accounted for the majority of test strip use. However, based on potential implementation of test strip limit policies, 95% of the reduction of test strip use is predicted to occur in the groups not using insulin. Based on current trends, the 5-year predicted additional cost associated with not implementing a test strip limit policy similar to that implemented in other Canadian provinces was estimated to be a total of $12.35 million.

IMPLICATIONS

Implementation of the guideline-based policy limits is predicted to produce considerable savings, with 95% of potential savings occurring in patients not using insulin. There is, therefore, a significant opportunity cost associated with not implementing a policy to reduce BGTS utilization by patients with diabetes in Manitoba. Based on the lack of evidence to suggest significant outcome improvements with long-term frequent SMBG by patients not using insulin, more selective use of test strips for SMBG could allow for significant cost savings that could be redirected to other programs and interventions for the growing population of patients with diabetes in Manitoba.

摘要

目的

最近,人们对血糖自我监测(SMBG)的频率、益处及成本进行了重新评估。由于几乎没有证据表明频繁进行血糖自我监测对未使用胰岛素的糖尿病患者有益,因此在加拿大各辖区已提出并实施了新的指南及试纸限购政策,以促进更具选择性的血糖自我监测实践。本研究的目的是评估2000年至2013年曼尼托巴省血糖自我监测所用试纸和采血针的总体使用情况及成本,并探讨实施试纸数量限制的政策影响及其对总体成本和政府成本的影响。

方法

对2000年至2013年曼尼托巴省所有糖尿病患者的血糖试纸(BGTSs)和采血针处方申请进行了分析。每年,根据最强化的糖尿病治疗方法,将患者分为4个相互排斥的分层组。评估每年每组的试纸和采血针使用情况及成本,并使用自回归积分移动平均模型预测实施血糖试纸限制政策可能节省的成本。

结果

2000年,曼尼托巴省发放了800万条试纸,到2013年增加了170%,达到2170万条。使用胰岛素的患者占试纸使用量的大部分。然而,基于试纸限制政策的潜在实施情况,预计95%的试纸使用量减少将发生在未使用胰岛素的组中。根据当前趋势,预计与不实施类似于加拿大其他省份实施的试纸限制政策相关的5年额外成本总计为1235万美元。

启示

预计实施基于指南的政策限制将节省大量资金,95%的潜在节省将发生在未使用胰岛素的患者中。因此,在曼尼托巴省,不实施减少糖尿病患者血糖试纸使用量的政策存在重大机会成本。鉴于缺乏证据表明未使用胰岛素的患者长期频繁进行血糖自我监测能显著改善治疗效果,更具选择性地使用血糖试纸进行自我监测可实现显著的成本节省,这些节省的资金可重新用于曼尼托巴省不断增加的糖尿病患者群体的其他项目和干预措施。

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