Pavan Nicola, Zargar Homayoun, Sanchez-Salas Rafael, Castillo Octavio, Celia Antonio, Gallo Gaetano, Sivaraman Arjun, Cathelineau Xavier, Autorino Riccardo
Urology Institute, University Hospitals, Cleveland, OH; Urology Clinic, Department of Medical, Surgical and Health Science, University of Trieste, Italy.
Department of Urology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Urology. 2016 May;91:104-10. doi: 10.1016/j.urology.2016.02.032. Epub 2016 Mar 3.
To report a comparative analysis of laparoscopic simple prostatectomy (LSP) vs robot-assisted simple prostatectomy (RASP).
Consecutive cases of LSP and RASP done between 2003 and 2014 at 3 participating institutions were included in this retrospective analysis. The effectiveness of the two procedures was determined by performing a paired analysis of main functional and surgical outcomes. A multivariate analysis was also conducted to determine the factors predictive of "trifecta" outcome (combination of International Prostate Symptom Score <8, Qmax > 15 mL/second, and no perioperative complications).
A total of 319 patients underwent minimally invasive simple prostatectomy at the participating institutions over the study period. Total prostate volume was larger in the RASP group (median 118.5 mL vs 109 mL, P = .02). Median estimated blood loss tended to be higher for LSP (300 mL vs 350 mL, P = .07). There was no difference in terms of catheterization time (P = .3) and hospital stay (P = .42). A higher rate of overall postoperative complications was recorded in the RASP group (17.7% vs 5.3%), but rate of major complications was not significantly different between the two techniques (2.3 vs 2.1, P = .6). Subjective and objective parameters significantly improved for both LSP and RASP. On multivariable analysis, only two factors were associated with likelihood of obtaining a favorable (trifecta) outcome: age (odds ratio: 0.94; P = .03) and body mass index (odds ratio: 0.84; P = .03).
Both LSP and RASP can be regarded as safe and effective minimally invasive surgical treatments for bladder outlet obstruction due to large prostate glands.
报告腹腔镜单纯前列腺切除术(LSP)与机器人辅助单纯前列腺切除术(RASP)的对比分析。
本回顾性分析纳入了2003年至2014年期间在3家参与机构进行的连续LSP和RASP病例。通过对主要功能和手术结果进行配对分析来确定两种手术的有效性。还进行了多变量分析以确定预测“三连胜”结局(国际前列腺症状评分<8、最大尿流率>15毫升/秒且无围手术期并发症的组合)的因素。
在研究期间,共有319例患者在参与机构接受了微创单纯前列腺切除术。RASP组的前列腺总体积更大(中位数118.5毫升对109毫升,P = 0.02)。LSP的估计失血量中位数往往更高(300毫升对350毫升,P = 0.07)。导尿时间(P = 0.3)和住院时间(P = 0.42)方面无差异。RASP组记录的总体术后并发症发生率更高(17.7%对5.3%),但两种技术的主要并发症发生率无显著差异(2.3对2.1,P = 0.6)。LSP和RASP的主观和客观参数均有显著改善。多变量分析显示,只有两个因素与获得良好(三连胜)结局的可能性相关:年龄(比值比:0.94;P = 0.03)和体重指数(比值比:0.84;P = 0.03)。
对于因前列腺肿大导致的膀胱出口梗阻,LSP和RASP均可视为安全有效的微创手术治疗方法。