Suppr超能文献

[哮喘持续状态的治疗。71例静脉应用β-肾上腺素能支气管扩张剂治疗的经验]

[Treatment of status asthmaticus. Experience of intravenous beta-adrenergic bronchodilator therapy in 71 cases].

作者信息

Escribano Subias J, Sanz Manrique N, Morales Hidalgo V, Clofent Vilaplana R, Iglesias Berenguer J, Roqueta Mas J, Eseverri Asin J L

机构信息

Hospital Infantil Valle del Hebrón, Barcelona.

出版信息

An Esp Pediatr. 1989 Nov;31(5):435-9.

PMID:2694871
Abstract

A retrospective study of the patients admitted during the last 8 years with status asthmaticus is reported. We compare the requirement of mechanical ventilation with the beta-agonist therapy received and the type of asthma. About 71 patients admitted, 67% were IgE dependent asthmatic (EDA) children and 31% no-IgE dependent asthmatic (nEDA) ones. They needed intermittent positive pressure ventilation (IPPV) in 20 instances; no difference was found between both types of asthma. We studied the ventilatory parameters used. The 33% of EDA children was treated using a continuous IV infusion of hexoprenalina, requiring IPPV in 5 (31%) of them. The rest received a continuous IV of isoproterenol, and only the 16% required IPPV. We found isoproterenol to be more effective than hexoprenalina in the treatment of status asthmaticus. Similar results were obtained with the nEDA group. The Downes score was showed to be a good predictor-index scoring system in many cases.

摘要

本文报道了一项对过去8年中收治的哮喘持续状态患者的回顾性研究。我们比较了机械通气需求与所接受的β-受体激动剂治疗以及哮喘类型之间的关系。在大约71例入院患者中,67%为IgE依赖型哮喘(EDA)儿童,31%为非IgE依赖型哮喘(nEDA)患者。他们中有20例需要间歇性正压通气(IPPV);两种类型的哮喘之间未发现差异。我们研究了所使用的通气参数。33%的EDA儿童采用六甲双铵持续静脉输注治疗,其中5例(31%)需要IPPV。其余患者接受异丙肾上腺素持续静脉输注,只有16%需要IPPV。我们发现异丙肾上腺素在治疗哮喘持续状态方面比六甲双铵更有效。nEDA组也获得了类似的结果。在许多情况下,唐斯评分被证明是一个良好的预测指标评分系统。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验