Escribano Subias J, Sanz Manrique N, Morales Hidalgo V, Clofent Vilaplana R, Iglesias Berenguer J, Roqueta Mas J, Eseverri Asin J L
Hospital Infantil Valle del Hebrón, Barcelona.
An Esp Pediatr. 1989 Nov;31(5):435-9.
A retrospective study of the patients admitted during the last 8 years with status asthmaticus is reported. We compare the requirement of mechanical ventilation with the beta-agonist therapy received and the type of asthma. About 71 patients admitted, 67% were IgE dependent asthmatic (EDA) children and 31% no-IgE dependent asthmatic (nEDA) ones. They needed intermittent positive pressure ventilation (IPPV) in 20 instances; no difference was found between both types of asthma. We studied the ventilatory parameters used. The 33% of EDA children was treated using a continuous IV infusion of hexoprenalina, requiring IPPV in 5 (31%) of them. The rest received a continuous IV of isoproterenol, and only the 16% required IPPV. We found isoproterenol to be more effective than hexoprenalina in the treatment of status asthmaticus. Similar results were obtained with the nEDA group. The Downes score was showed to be a good predictor-index scoring system in many cases.
本文报道了一项对过去8年中收治的哮喘持续状态患者的回顾性研究。我们比较了机械通气需求与所接受的β-受体激动剂治疗以及哮喘类型之间的关系。在大约71例入院患者中,67%为IgE依赖型哮喘(EDA)儿童,31%为非IgE依赖型哮喘(nEDA)患者。他们中有20例需要间歇性正压通气(IPPV);两种类型的哮喘之间未发现差异。我们研究了所使用的通气参数。33%的EDA儿童采用六甲双铵持续静脉输注治疗,其中5例(31%)需要IPPV。其余患者接受异丙肾上腺素持续静脉输注,只有16%需要IPPV。我们发现异丙肾上腺素在治疗哮喘持续状态方面比六甲双铵更有效。nEDA组也获得了类似的结果。在许多情况下,唐斯评分被证明是一个良好的预测指标评分系统。