Day Alexander C, Lau Nicola M, Stevens Julian D
From Moorfields Eye Hospital (Day, Lau, Stevens), and the NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology (Day), London, UK.
From Moorfields Eye Hospital (Day, Lau, Stevens), and the NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology (Day), London, UK.
J Cataract Refract Surg. 2016 Jan;42(1):102-9. doi: 10.1016/j.jcrs.2015.07.045.
To describe the effect of femtosecond laser intrastromal astigmatic keratotomy (AK) performed during cataract surgery.
Moorfields Eye Hospital, London, United Kingdom.
Prospective case series.
This study comprised patients having laser cataract surgery with concurrent astigmatism management by intrastromal AK. All eyes had greater than 0.7 corneal diopter (D) cylinder. An intrastromal AK nomogram with 8.0 mm diameter paired symmetric limbal centered arcs was used. Corneal keratometry was measured preoperatively and 1 month postoperatively using a KR8100PA topographer-autorefractor. Astigmatic analyses were performed using the Alpins method considering 3 vectors-target induced astigmatism (TIA), surgically induced astigmatism (SIA) and difference vector (DV)-and calculation of coupling measures.
In all, 196 eyes of 133 patients were analyzed. The mean TIA (equivalent to preoperative corneal cylinder) was 1.21 D ± 0.42 (SD) (range 0.75 to 2.64 D) and the mean SIA was 0.74 DC ± 0.40 (range 0.00 to 2.86). The mean difference vector was 0.74 ± 0.38 D (range 0.00 to 2.25 D). The mean correction index was 0.63 ± 0.32 (range 0.00 to 1.93), indicating that the mean astigmatism correction was 63%. Fourteen eyes (7.1%) and 7 eyes (3.6%) had an astigmatism correction of greater than 100% and greater than 120%, respectively. Overall 0%, 48.5%, and 51.5% of eyes had 0.50 D or less, 1.0 D or less, or greater than 1.0 D, respectively, preoperatively compared with 32.1%, 85.7%, and 14.3%, postoperatively. There were no cases of corneal endothelial perforation or inadvertent placement within the visual axis.
The intrastromal AKs were easily programmed as an integral part of laser-assisted cataract surgery without additional cost, significantly reduced corneal cylinder, and appeared to be safe through 1 month of follow-up.
Dr. Day was supported by the National Institute for Health Research (NIHR) Biomedical Research Centre based at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology. Dr. Stevens has been a consultant to Optimedica Inc., now part of Abbott Medical Optics.
描述在白内障手术期间进行飞秒激光基质内散光性角膜切开术(AK)的效果。
英国伦敦摩尔菲尔德眼科医院。
前瞻性病例系列。
本研究纳入了接受激光白内障手术并同时通过基质内AK进行散光治疗的患者。所有眼睛的角膜散光度数均大于0.7屈光度(D)。使用直径为8.0 mm的配对对称角膜缘中心弧的基质内AK列线图。术前及术后1个月使用KR8100PA地形仪-自动验光仪测量角膜曲率。采用阿尔平斯方法进行散光分析,考虑3个矢量——目标诱导散光(TIA)、手术诱导散光(SIA)和差异矢量(DV)——并计算耦合测量值。
共分析了133例患者的196只眼。平均TIA(相当于术前角膜散光)为1.21 D±0.42(标准差)(范围为0.75至2.64 D),平均SIA为0.74 DC±0.40(范围为0.00至2.86)。平均差异矢量为0.74±0.38 D(范围为0.00至2.25 D)。平均矫正指数为0.63±0.32(范围为0.00至1.93),表明平均散光矫正率为63%。分别有14只眼(7.1%)和7只眼(3.6%)的散光矫正率大于100%和大于120%。总体而言,术前分别有0%、48.5%和51.5%的眼睛散光度数为0.50 D或更低、1.0 D或更低或大于1.0 D,术后分别为32.1%、85.7%和14.3%。没有角膜内皮穿孔或在视轴内意外植入的病例。
基质内AK可轻松编程为激光辅助白内障手术的一个组成部分,无需额外费用,显著降低了角膜散光,并且在1个月的随访期内似乎是安全的。
戴博士得到了基于摩尔菲尔德眼科医院国民保健服务基金会信托基金和伦敦大学学院眼科研究所的国家卫生研究院(NIHR)生物医学研究中心的支持。史蒂文斯博士曾是Optimedica公司(现为雅培医疗光学公司的一部分)的顾问。