Meyer P, Methlin G, Untereiner M
Praticiens hospitaliers, CHR, Metz Thionville.
Ann Otolaryngol Chir Cervicofac. 1989;106(8):567-76.
From 1975 to 1982, 73 cases of nasopharyngeal carcinoma were treated in Strasbourg (Centre Paul Strauss) and Metz (CHR Bon Secours). 34.1% of the patients were of maghrebine origin, the others were europeans. Two histological types were studied: undifferentiated carcinomas of UCNT type, spinocellulars carcinomas of CS type. 60.3% of the patients had T3 and T4 stages, and only 27.4% of the patients had no pathological nodal. As to treatment, radiotherapy is the best choice, because of the deep situation and the frequent involvement of nodals in the nasopharyngeal carcinoma. Taking into account the level of radiation doses, complications remain acceptable. The rate of overall failure is 51.3% at 3 years. The prognostic factors are essentially linked with sex, age, tumor site, site, histological type, T stage of UICC classification and TNM of the same classification, N stage of HO classification, and evaluation of treatment response realised at 4 months. The crude overall survival rate is 52% for patients of the serie.
1975年至1982年期间，斯特拉斯堡（保罗·施特劳斯中心）和梅斯（博勒库尔地区医院）共治疗了73例鼻咽癌患者。34.1%的患者来自马格里布地区，其余为欧洲人。研究了两种组织学类型：UCNT型未分化癌、CS型棘细胞癌。60.3%的患者处于T3和T4期，只有27.4%的患者没有病理性淋巴结转移。至于治疗，放疗是最佳选择，因为鼻咽癌位置深且淋巴结常受累。考虑到放射剂量水平，并发症仍在可接受范围内。3年时的总失败率为51.3%。预后因素主要与性别、年龄、肿瘤部位、组织学类型、国际抗癌联盟（UICC）分类的T期和同一分类的TNM、HO分类的N期以及4个月时的治疗反应评估有关。该系列患者的粗总生存率为52%。
