Ramji Ramesh, Khan Nafeesa T, Muñoz-Rojas Andrés, Miller-Jensen Kathryn
Department of Biomedical Engineering, Yale University, New Haven, Connecticut, USA-06511.
RSC Adv. 2015;5(81):66294-66300. doi: 10.1039/C5RA09056C. Epub 2015 Aug 4.
We describe a "pop-slide" patterning approach to easily produce thin film microstructures on the surface of glass with varying feature sizes (3 μm - 250 μm) and aspect ratios (0.066 - 3) within 45 minutes. This low cost method does not require specialized equipment while allowing us to produce micro structured gasket layers for sandwich assays and could be readily applied to many biological applications.
我们描述了一种“弹出-滑动”图案化方法,可在45分钟内轻松在玻璃表面制备具有不同特征尺寸(3μm - 250μm)和纵横比(0.066 - 3)的薄膜微结构。这种低成本方法不需要专门设备,同时使我们能够生产用于夹心分析的微结构化垫片层,并且可很容易地应用于许多生物应用中。