Ackerman Michael, Atkins Dianne L, Triedman John K
From Departments of Internal Medicine, Pediatrics, and Molecular Pharmacology & Experimental Therapeutics; Divisions of Cardiovascular Diseases and Pediatric Cardiology; Windland Smith Rice Sudden Death Genomics Laboratory; Mayo Clinic, Rochester, MN (M.A.);Stead Family Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa, City (D.L.A.); andDepartment of Cardiology, Boston Children's Hospital, MA (J.K.T.).
Circulation. 2016 Mar 8;133(10):1006-26. doi: 10.1161/CIRCULATIONAHA.115.020254.
Although the occurrence of sudden cardiac death (SCD) in a young person is a rare event, it is traumatic and often widely publicized. In recent years, SCD in this population has been increasingly seen as a public health and safety issue. This review presents current knowledge relevant to the epidemiology of SCD and to strategies for prevention, resuscitation, and identification of those at greatest risk. Areas of active research and controversy include the development of best practices in screening, risk stratification approaches and postmortem evaluation, and identification of modifiable barriers to providing better outcomes after resuscitation of young SCD patients. Institution of a national registry of SCD in the young will provide data that will help to answer these questions.
尽管年轻人发生心源性猝死(SCD)是罕见事件,但它具有创伤性且常常被广泛报道。近年来,这一人群中的SCD越来越被视为一个公共卫生和安全问题。本综述介绍了与SCD流行病学以及预防、复苏和识别高危人群策略相关的当前知识。积极研究和存在争议的领域包括筛查最佳实践的发展、风险分层方法和尸检评估,以及识别在年轻SCD患者复苏后改善预后的可改变障碍。建立全国性的年轻人心源性猝死登记册将提供有助于回答这些问题的数据。