Chen Szu-Han, Lee Meng-Chang, Wang Po-Yuan, Chu Yen-Ju, Liu Hsin-Ming, Wu Jhong-Lin, Hsieh Ming-Ju, Ma Matthew Huei-Ming, Chiang Wen-Chu, Tseng Wei-Chieh
Department of Emergency Medicine, National Taiwan University Hospital, No. 7, Chung-Shan South Road, Taipei, Taiwan.
Department of Emergency Medicine, National Taiwan University Hospital Yunlin Branch, No. 579, Sec. 2, Yunlin Rd., Douliu City, Yunlin County, Taiwan.
Pediatr Res. 2025 Aug 7. doi: 10.1038/s41390-025-04295-4.
The role of emergency medical services (EMS) in out-of-hospital cardiac arrest (OHCA) among children and young adults remains understudied. This study evaluated EMS utilization and its association with outcomes in non-traumatic pediatric and young adult OHCA.
Patients aged <35 years with non-traumatic OHCA treated at a tertiary center between 1995 and 2019 were analyzed. Exclusion criteria included referrals and newborns <24 hours old. EMS use was defined as public-ambulance transport to the emergency department. The primary outcome was return of spontaneous circulation (ROSC).
Of 195 OHCAs, 109 (55.9%) were pediatric. EMS use increased with age, from 38.0% (0-5 years) to 82.6% (18 to <35 years). EMS was associated with higher ROSC and survival to hospital discharge (41.7% vs. 24.6%, p = 0.06, and 25.0% vs. 6.6%, p = 0.007, respectively) in pediatric group but not in the young adult group. However, EMS improved the ROSC rate in young adults from 30.8% during 1995-2002 to 65.7% during 2011-2019. The impact of EMS was not significant after multivariable adjustment.
EMS utilization and clinical outcomes in pediatric and young adults OHCA remained suboptimal over the 25-year study period. Targeted advocacy and education are essential to strengthen the chain of survival in these population.
Pediatric OHCA patients had significantly lower EMS use than young adults. EMS was associated with higher ROSC and survival to hospital discharge in the pediatric group but not in the young adult group. While EMS-transported young adults showed improved outcomes over time, pediatric outcomes remained unchanged. Pediatric OHCA patients transported by EMS had shorter scene times and received fewer prehospital interventions than young adults. Educating caregivers on the importance of EMS activation is crucial. Emergency departments must be prepared for unannounced pediatric cases. There is an urgent need for protocols specifically tailored to pediatric OHCA care.
儿童和青年院外心脏骤停(OHCA)中紧急医疗服务(EMS)的作用仍未得到充分研究。本研究评估了非创伤性儿科和青年OHCA中EMS的使用情况及其与预后的关联。
分析了1995年至2019年在一家三级中心接受治疗的年龄<35岁的非创伤性OHCA患者。排除标准包括转诊病例和出生<24小时的新生儿。EMS使用定义为使用公共救护车转运至急诊科。主要结局是自主循环恢复(ROSC)。
在195例OHCA中,109例(55.9%)为儿科患者。EMS的使用随年龄增加,从38.0%(0至5岁)增至82.6%(18至<35岁)。在儿科组中,EMS与更高的ROSC及存活至出院相关(分别为41.7%对24.6%,p = 0.06;25.0%对6.6%,p = 0.007),但在青年组中无此关联。然而,EMS使青年组的ROSC率从1995 - 2002年期间的30.8%提高至2011 - 2019年期间的65.