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瘤内注射普萘洛尔联合复方倍他米松治疗婴幼儿血管瘤

Treatment of infantile hemangioma by intralesional injection of propranolol combined with compound betamethasone.

作者信息

Shao R-Z, Zhao D-H, Li J

机构信息

Pharmacy Department, Jinan Military General Hospital, Jinan, China.

出版信息

Eur Rev Med Pharmacol Sci. 2016;20(4):751-5.

Abstract

OBJECTIVE

To explore the effective and convenient methods of infantile hemangioma treatment.

PATIENTS AND METHODS

From October 2010 to June 2014, 31 infantile hemangioma patients admitted to our hospital, were administered propranolol combined with betamethasone injection treatment of lesions.

RESULTS

All patients were followed for 6 months-2 years. In treated patients, 24 patients with tumor had complete or nearly complete remission while 6 patients showed partial regression. In 1 patient the tumor had no evident change. Adverse reactions of the therapy included local tissue atrophy, ulcer and anorexia, mild diarrhea in the early treatment. Ulcer wound healed after dressing change.

CONCLUSIONS

Treatment of infantile hemangioma lesions with an injection of propranolol combined with betamethasone showed good efficacy. The method is safe and reliable with clear curative effect, convenient, less complicated, and especially suitable for patients with a small area infantile hemangioma.

摘要

目的

探讨治疗婴幼儿血管瘤有效且便捷的方法。

患者与方法

2010年10月至2014年6月,我院收治的31例婴幼儿血管瘤患者,采用普萘洛尔联合倍他米松注射治疗病灶。

结果

所有患者随访6个月至2年。治疗的患者中,24例肿瘤完全或接近完全缓解,6例部分消退。1例患者肿瘤无明显变化。治疗的不良反应包括局部组织萎缩、溃疡和厌食,治疗初期有轻度腹泻。换药后溃疡创面愈合。

结论

普萘洛尔联合倍他米松注射治疗婴幼儿血管瘤病灶疗效良好。该方法安全可靠,疗效确切,操作简便,并发症少,尤其适用于小面积婴幼儿血管瘤患者。

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