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纳曲酮/安非他酮缓释片(Contrave):肥胖成年人慢性体重管理的新获批治疗选择。

Naltrexone/Bupropion ER (Contrave): Newly Approved Treatment Option for Chronic Weight Management in Obese Adults.

作者信息

Sherman Matthew M, Ungureanu Sinziana, Rey Jose A

出版信息

P T. 2016 Mar;41(3):164-72.

PMID:26957883
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4771085/
Abstract

Naltrexone/bupropion ER (Contrave): newly approved treatment option for chronic weight management in obese adults.

摘要

纳曲酮/安非他酮缓释片(Contrave):肥胖成年人慢性体重管理新获批的治疗选择。

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Naltrexone/Bupropion ER (Contrave): Newly Approved Treatment Option for Chronic Weight Management in Obese Adults.纳曲酮/安非他酮缓释片(Contrave):肥胖成年人慢性体重管理的新获批治疗选择。
P T. 2016 Mar;41(3):164-72.
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本文引用的文献

1
Naltrexone/bupropion for obesity: an investigational combination pharmacotherapy for weight loss.纳曲酮/安非他酮用于治疗肥胖症:一种用于减肥的研究性联合药物疗法。
Pharmacol Res. 2014 Jun;84:1-11. doi: 10.1016/j.phrs.2014.04.004. Epub 2014 Apr 19.
2
Prevalence of childhood and adult obesity in the United States, 2011-2012.美国儿童和成人肥胖率,2011-2012 年。
JAMA. 2014 Feb 26;311(8):806-14. doi: 10.1001/jama.2014.732.
3
2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society.2013年美国心脏协会/美国心脏病学会/肥胖学会成人超重和肥胖管理指南:美国心脏病学会/美国心脏协会实践指南工作组及肥胖学会报告
J Am Coll Cardiol. 2014 Jul 1;63(25 Pt B):2985-3023. doi: 10.1016/j.jacc.2013.11.004. Epub 2013 Nov 12.
4
Effects of naltrexone sustained-release/bupropion sustained-release combination therapy on body weight and glycemic parameters in overweight and obese patients with type 2 diabetes.纳曲酮缓释/安非他酮缓释联合疗法对超重和肥胖2型糖尿病患者体重及血糖参数的影响
Diabetes Care. 2013 Dec;36(12):4022-9. doi: 10.2337/dc13-0234. Epub 2013 Oct 21.
5
Why do we need drugs to treat the patient with obesity?为什么我们需要用药物来治疗肥胖症患者?
Obesity (Silver Spring). 2013 May;21(5):893-9. doi: 10.1002/oby.20394.
6
A randomized, phase 3 trial of naltrexone SR/bupropion SR on weight and obesity-related risk factors (COR-II).纳曲酮缓释/安非他酮缓释片治疗体重和肥胖相关风险因素的随机、3 期临床试验(COR-II)。
Obesity (Silver Spring). 2013 May;21(5):935-43. doi: 10.1002/oby.20309.
7
ACS chemical neuroscience molecule spotlight on contrave.ACS 化学神经科学杂志特写:康百视。
ACS Chem Neurosci. 2011 Sep 21;2(9):484-6. doi: 10.1021/cn200076y.
8
Combination therapy with naltrexone and bupropion for obesity.纳曲酮与安非他酮联合治疗肥胖症。
Expert Opin Pharmacother. 2011 Aug;12(11):1813-26. doi: 10.1517/14656566.2011.591382. Epub 2011 Jun 21.
9
Differential expression and sensitivity of presynaptic and postsynaptic opioid receptors regulating hypothalamic proopiomelanocortin neurons.调节下丘脑促肾上腺皮质素释放激素神经元的突触前和突触后阿片受体的差异表达和敏感性。
J Neurosci. 2011 Jan 5;31(1):281-8. doi: 10.1523/JNEUROSCI.4654-10.2011.
10
Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.纳曲酮联合安非他酮对超重和肥胖成年人体重减轻的影响(COR-I):一项多中心、随机、双盲、安慰剂对照、3 期临床试验。
Lancet. 2010 Aug 21;376(9741):595-605. doi: 10.1016/S0140-6736(10)60888-4. Epub 2010 Jul 29.