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新型肥胖症治疗方法:海藻作为替代医学与最新常规疗法联合应用。

Novel Therapeutic Approach for Obesity: Seaweeds as an Alternative Medicine with the Latest Conventional Therapy.

机构信息

Department of Dialysis Technology, Sharda School of Allied Health Science, Sharda University, Greater Noida 201310, Uttar Pradesh, India.

Department of Physiology, All India Institute of Medical Science, New Delhi 110029, India.

出版信息

Med Sci (Basel). 2024 Oct 13;12(4):55. doi: 10.3390/medsci12040055.

Abstract

The prevalence of overweight and obesity is increasing worldwide. Common comorbidities related to obesity, significantly polygenic disorders, cardiovascular disease, and heart conditions affect social and monetary systems. Over the past decade, research in drug discovery and development has opened new paths for alternative and conventional medicine. With a deeper comprehension of its underlying mechanisms, obesity is now recognized more as a chronic condition rather than merely a result of lifestyle choices. Nonetheless, addressing it solely through lifestyle changes is challenging due to the intricate nature of energy regulation dysfunction. The Federal Drug Administration (FDA) has approved six medications for the management of overweight and obesity. Seaweed are plants and algae that grow in oceans, rivers, and lakes. Studies have shown that seaweed has therapeutic potential in the management of body weight and obesity. Seaweed compounds such as carotenoids, xanthophyll, astaxanthin, fucoidans, and fucoxanthin have been demonstrated as potential bioactive components in the treatment of obesity. The abundance of natural seaweed bioactive compounds has been explored for their therapeutic potential for treating obesity worldwide. Keeping this view, this review covered the latest developments in the discovery of varied anti-obese seaweed and its bioactive components for the management of obesity.

摘要

超重和肥胖的患病率在全球范围内不断上升。与肥胖相关的常见合并症,如多种遗传疾病、心血管疾病和心脏疾病,会影响社会和货币系统。在过去的十年中,药物发现和开发方面的研究为替代和传统医学开辟了新的道路。由于对其潜在机制有了更深入的理解,肥胖现在被更多地视为一种慢性疾病,而不仅仅是生活方式选择的结果。然而,由于能量调节功能障碍的复杂性,仅通过生活方式改变来解决这个问题具有挑战性。美国食品和药物管理局 (FDA) 已批准六种用于管理超重和肥胖的药物。海藻是生长在海洋、河流和湖泊中的植物和藻类。研究表明,海藻在管理体重和肥胖方面具有治疗潜力。海藻化合物,如类胡萝卜素、叶黄素、虾青素、褐藻胶和岩藻黄质,已被证明是治疗肥胖的潜在生物活性成分。世界各地都在探索天然海藻生物活性化合物的丰富性,以挖掘其治疗肥胖的潜力。基于这一观点,本综述涵盖了发现各种抗肥胖海藻及其生物活性成分以管理肥胖症的最新进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f38a/11503287/02518803d056/medsci-12-00055-g001.jpg

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