尼日利亚一家教学医院中镰状细胞病患者脾脏的超声评估
Sonographic evaluation of the spleen among sickle cell disease patients in a teaching hospital in Nigeria.
作者信息
Eze Charles Ugwoke, Offordile Godfrey Chukwudi, Agwuna Kennedy Kenechukwu, Ocheni Sunday, Nwadike Inoccent Uchechukwu, Chukwu Bartholomew Friday
机构信息
Medical Radiography and Radiological Sciences, University of Nigeria, Enugu Campus, Enugu State, Nigeria.
Radiation Medicine, University of Nigeria, Enugu Campus, Enugu State, Nigeria.
出版信息
Afr Health Sci. 2015 Sep;15(3):949-58. doi: 10.4314/ahs.v15i3.32.
BACKGROUND
Regional variations in size and parenchyma echo-texture of the spleen among sickle cell disease (SCD) patients have been documented in various publications. The objectives of this study were to assess the size and parenchyma echo-texture of the spleen of SCD patients and ascertain the relationship of age, height and weight with the spleen sizes.
METHODS
This was a cross sectional study involving 103 each of SCD and age matched control subjects. Aloka ST- 550 -3500 ultrasound machine with 3.5 and 5 MHz convex transducers was used to scan the subjects over a 15 months period (September, 2012 to November, 2013). The age, height and weight of each subject were recorded.
RESULTS
The spleen sizes of SCD patients were generally larger than those of the controls (p < 0.05). Abnormal spleen parenchyma of varied appearances was found among the SCD subjects. There were negative correlations between mean spleen sizes and height, weight and age in SCD patients but positive correlations were found between them in the controls.
CONCLUSION
Routine sonographic assessment of spleen size and echo-texture is useful in the management of SCD patients.
背景
镰状细胞病（SCD）患者脾脏大小及实质回声纹理的区域差异已在各类出版物中有所记载。本研究的目的是评估SCD患者脾脏的大小及实质回声纹理，并确定年龄、身高和体重与脾脏大小之间的关系。
方法
这是一项横断面研究，纳入了103例SCD患者及年龄匹配的对照受试者。在15个月期间（2012年9月至2013年11月），使用配备3.5 MHz和5 MHz凸阵探头的Aloka ST-550 -3500超声仪对受试者进行扫描。记录每位受试者的年龄、身高和体重。
结果
SCD患者的脾脏大小总体上大于对照组（p < 0.05）。在SCD受试者中发现了外观各异的异常脾脏实质。SCD患者的平均脾脏大小与身高、体重和年龄呈负相关，但在对照组中呈正相关。
结论
对脾脏大小和回声纹理进行常规超声评估有助于SCD患者的管理。
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