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早期人工破膜对自然分娩结局的影响:尼日利亚东南部埃努古孕妇的一项随机对照试验

Effect of early amniotomy on the outcome of spontaneous labour: a randomized controlled trial of pregnant women in Enugu, South-east Nigeria.

作者信息

Onah Livinus N, Dim Cyril C, Nwagha Uchenna I, Ozumba Benjamin C

机构信息

Departments of Obstetrics and Gynaecology, College of Medicine Enugu State University of Science and Technology, Enugu Nigeria.

Departments of Obstetrics and Gynaecology, College of Medicine University of Nigeria Enugu Campus, Nigeria.

出版信息

Afr Health Sci. 2015 Dec;15(4):1097-103. doi: 10.4314/ahs.v15i4.7.

Abstract

BACKGROUND

Early amniotomy is common in obstetric practice but, its effectiveness has not been proven.

OBJECTIVES

To determine the effects of early amniotomy on the duration of labour, and other maternal / neonatal outcomes of uncomplicated pregnancies in Enugu, South-east Nigeria.

METHODS

A randomized controlled study of 214 consenting term pregnant women at the University of Nigeria Teaching Hospital Enugu, Nigeria. Intervention group received amniotomy early in active labour while the control group had their membranes conserved.

RESULTS

Mean duration of labour for the amniotomy group (279.4 ± 53.7 minutes) was significantly lower than that of control group (354.4 ± 67.5 minutes), (t = -8.988, p <0.001). Three (3.8%) women in amniotomy group needed oxytocin augmentation as against 21 (19.6%) women in the control group RR = 0.14, (CI 95%: 0.04 - 0.46), NNT = 16. The two groups did not vary with respect to cesarean section rate, newborn Apgar scores, and need for new born special care unit admission.

CONCLUSION

Early amniotomy when compared to fetal membrane conservation reduced the duration of labour and need for oxytocin augmentation among term singleton pregnant women in Enugu, Nigeria. Its routine use in well selected cases may reduce prolonged labour and its complications.

摘要

背景

早期人工破膜在产科实践中很常见,但其有效性尚未得到证实。

目的

确定早期人工破膜对尼日利亚东南部埃努古地区无并发症妊娠的产程及其他母儿结局的影响。

方法

在尼日利亚埃努古的尼日利亚大学教学医院对214名同意参与的足月孕妇进行随机对照研究。干预组在活跃期早期接受人工破膜,而对照组胎膜保持完整。

结果

人工破膜组的平均产程(279.4±53.7分钟)显著低于对照组(354.4±67.5分钟),(t=-8.988,p<0.001)。人工破膜组有3名(3.8%)妇女需要使用缩宫素加强宫缩,而对照组有21名(19.6%)妇女需要,相对危险度RR=0.14,(95%可信区间:0.04 - 0.46),需治疗人数NNT=16。两组在剖宫产率、新生儿阿氏评分以及新生儿入住特殊护理病房的需求方面无差异。

结论

与保留胎膜相比,早期人工破膜可缩短尼日利亚埃努古地区足月单胎孕妇的产程,并减少缩宫素加强宫缩的需求。在精心挑选的病例中常规使用早期人工破膜可能会减少产程延长及其并发症。

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Amniotomy for shortening spontaneous labour.人工破膜以缩短自然产程。
Cochrane Database Syst Rev. 2013 Jun 18;2013(6):CD006167. doi: 10.1002/14651858.CD006167.pub4.
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The less studied effects of Amniotomy.人工破膜研究较少的影响。
J Matern Fetal Neonatal Med. 2013 Nov;26(17):1687-90. doi: 10.3109/14767058.2013.798286. Epub 2013 May 28.
3
Amniotomy for shortening spontaneous labour.人工破膜以缩短自然产程。
Cochrane Database Syst Rev. 2013 Jan 31(1):CD006167. doi: 10.1002/14651858.CD006167.pub3.
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Pregnant Nigerian women's view of cesarean section.尼日利亚孕妇对剖宫产的看法。
Niger J Clin Pract. 2011 Jul-Sep;14(3):276-9. doi: 10.4103/1119-3077.86766.
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Does a preference for symphysiotomy over caesarean section reduce the operative delivery rate?
Trop Doct. 2009 Oct;39(4):198-200. doi: 10.1258/td.2009.080070.
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ACOG Practice Bulletin No. 107: Induction of labor.美国妇产科医师学会实践公告第107号:引产
Obstet Gynecol. 2009 Aug;114(2 Pt 1):386-397. doi: 10.1097/AOG.0b013e3181b48ef5.
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Active management of labor: does it make a difference?活跃产程管理:有区别吗?
Am J Obstet Gynecol. 1997 Sep;177(3):599-605. doi: 10.1016/s0002-9378(97)70152-2.

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