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[一种新型硫胺化合物(苯甲酰氧基甲基硫胺)治疗口腔颌面外科手术后疼痛症状的疗效及耐受性评估]

[Evaluation of the therapeutic efficacy and tolerance of a new thiamine compound (benzoyloxymethylthiamine) in the treatment of postoperative pain symptomatology in odontostomatological surgery].

作者信息

Sammartino G, Nicolò M, Battagliese G, Amato M

出版信息

Minerva Stomatol. 1989 Nov;38(11):1201-3.

PMID:2695820
Abstract

The therapeutic effectiveness of benzoyloxymethyl-thiamin in controlling post-operative pain in odontostomatological surgery has been examined. The double blind study used a placebo and concerned 100 patients subjected to avulsion of the third molar in dysodontiasis on an out-patient basis. The results point to the effectiveness of benzoyloxymethyl-thiamin in the symptomatic treatment of post-operative pain symptomatology both as regards its duration and intensity; the drug also proved to be very well tolerated and its administration was not accompanied by any unwanted side-effects.

摘要

已对苯甲酰氧基甲基硫胺在控制口腔颌面外科手术后疼痛方面的治疗效果进行了研究。这项双盲研究使用了安慰剂,涉及100名门诊患者,这些患者因牙列紊乱接受了第三磨牙拔除术。结果表明,苯甲酰氧基甲基硫胺在术后疼痛症状的对症治疗中,无论是在持续时间还是强度方面都有效果;该药物耐受性也非常好,给药时未伴随任何不良副作用。

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