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使用生物电阻抗分析评估接受重症监护的早产儿的身体成分

ASSESSMENT OF BODY COMPOSITION USING BIOELECTRICAL IMPEDANCE ANALYSIS IN PRETERM NEONATES RECEIVING INTENSIVE CARE.

作者信息

Mól Nina, Kwinta Przemko

出版信息

Dev Period Med. 2015 Jul-Sep;19(3 Pt 1):297-304.

PMID:26958693
Abstract

AIM

Evaluation of bioelectrical impedance values and body composition during early infancy in groups of preterm newborns and full-term newborns.

MATERIAL AND METHODS

A total of 38 newborns was enrolled in the study: 26 very low birth weight preterm newborns with the mean birth weight of 1236 g (SD: 161) as the study group and 12 term newborns with birth weight of 2500-4000 g as the control group. Anthropometric measurements and body composition using bioimpedance analysis at the age of 1 week and at the age of 3 months were assessed.

RESULTS

At the age of 1 week we noted higher resistance with the impedance variables R5, R50 R100 in the group of preterm newborns compared to the full-term newborns' group (923(144) vs. 647(78) p < 0.01; 870 (140) vs. 615 (73) p < 0.01; 844 (141) vs. 599 (72) p < 0.01). Moreover, the bioimpedance index and fat mass (%) were significantly lower in the group of preterm infants at the age of 3 months (3.81 (0.9) vs. 5.72 (1.1) p < 0.01; 16.1% (1.7) vs. 18.9% (2.7) p = 0.006). We observed a decreased amount of the percentage of total body water (TBW%) in both of the analyzed infant groups throughout the observational period. At the age of 3 months the amount of TBW % was similar in both groups (71.5% (7.03) vs. 70.8% (8.8) p = 0.8).

CONCLUSIONS

Bioimpedance analysis is a simple, non-invasive, repeatable method to estimate total body water, fat-free mass, and fat mass, both in term and preterm newborns. The study confirms differences in body composition between preterm newborns and full-term newborns. Moreover, we have shown that the differences are present until the end of the 3rd month of life, with the exception of the amount of water percentage (TBW %), which are similar in both groups.

摘要

目的

评估早产新生儿和足月新生儿群体在婴儿早期的生物电阻抗值和身体成分。

材料与方法

共有38名新生儿参与本研究:26名极低出生体重的早产新生儿,平均出生体重为1236克(标准差:161)作为研究组,12名出生体重为2500 - 4000克的足月新生儿作为对照组。在1周龄和3月龄时评估人体测量指标以及使用生物电阻抗分析评估身体成分。

结果

在1周龄时,我们发现早产新生儿组的阻抗变量R5、R50、R100的电阻高于足月新生儿组(923(144) 对比 647(78),p < 0.01;870 (140) 对比 615 (73),p < 0.01;844 (141) 对比 599 (72),p < 0.01)。此外,早产婴儿组在3月龄时的生物电阻抗指数和脂肪量(%)显著更低(3.81 (0.9) 对比 5.72 (1.1),p < 0.01;16.1% (1.7) 对比 18.9% (2.7),p = 0.006)。在整个观察期内,我们观察到两个分析的婴儿组中总体水百分比(TBW%)的量均下降。在3月龄时,两组的TBW%量相似(71.5% (7.03) 对比 70.8% (8.8),p = 0.8)。

结论

生物电阻抗分析是一种简单、无创、可重复的方法,用于评估足月和早产新生儿的总体水、去脂体重和脂肪量。该研究证实了早产新生儿和足月新生儿在身体成分上的差异。此外,我们已经表明,这种差异一直存在到生命的第3个月末,除了水百分比(TBW%)的量,两组相似。

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