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[某大学诊所由多重耐药性粘质沙雷氏菌引起的医院感染——临床情况及耐药性]

[Nosocomial infections caused by multi-resistant Serratia marcescens at a university clinic--clinical aspects and drug resistance].

作者信息

Halle E, Grauel E L, Klare I, Bollmann R, Buchholz P, Scholowska-Köhler W, Witte W, Göldner B, Baumann B

出版信息

Padiatr Grenzgeb. 1989;28(5):299-309.

PMID:2695885
Abstract

Serratia marcescens (S.m.) has become increasingly important as a nosocomial pathogen and displayed an increasing resistance to antimicrobial agents in the past decade. We recently studied in 1985 and 1986 an epidemic caused by multi resistant S.m. strains that involved 27 infants and 1 adult patient. 14 neonates (in most cases very low birth weight infants) in a neonatal intensive care unit developed a S.m.-septicemia and/or meningitis, 11 of them died. In a ward for young infants with congenital heart diseases 13 patients suffered a S.m. infection and one patient died in the adult intensive care unit in consequence of a S.m. septicemia.

摘要

粘质沙雷氏菌作为一种医院病原体变得越来越重要,并且在过去十年中对抗菌剂的耐药性不断增加。我们最近在1985年和1986年研究了由多重耐药粘质沙雷氏菌菌株引起的一次疫情,涉及27名婴儿和1名成年患者。一家新生儿重症监护病房的14名新生儿(大多数情况下为极低出生体重儿)发生了粘质沙雷氏菌败血症和/或脑膜炎,其中11人死亡。在一个患有先天性心脏病的幼儿病房,13名患者发生了粘质沙雷氏菌感染,一名成年重症监护病房的患者因粘质沙雷氏菌败血症死亡。

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