Venkateswaran Madhav, Unal Orhan, Hurley Samuel, Samsonov Alexey, Wang Peng, Fain Sean B, Kurpad Krishna N
IEEE Trans Biomed Eng. 2017 Jan;64(1):70-77. doi: 10.1109/TBME.2016.2538279. Epub 2016 Mar 4.
To model inductive coupling of endovascular coils with transmit RF excitation for selecting coils for MRI-guided interventions.
Independent and computationally efficient FEM models are developed for the endovascular coil, cable, transmit excitation, and imaging domain. Electromagnetic and circuit solvers are coupled to simulate net B + fields and induced currents and voltages. Our models are validated using the Bloch-Siegert B + mapping sequence for a series-tuned multimode coil, capable of tracking, wireless visualization, and high-resolution endovascular imaging.
Validation shows good agreement at 24-, 28-, and 34-μT background RF excitation within experimental limitations. Quantitative coil performance metrics agree with simulation. A parametric study demonstrates tradeoff in coil performance metrics when varying number of coil turns. Tracking, imaging, and wireless marker multimode coil features and their integration is demonstrated in a pig study.
Developed models for the multimode coil were successfully validated. Modeling for geometric optimization and coil selection serves as a precursor to time consuming and expensive experiments. Specific applications demonstrated include parametric optimization, coil selection for a cardiac intervention, and an animal imaging experiment.
Our modular, adaptable, and computationally efficient modeling approach enables rapid comparison, selection, and optimization of inductively coupled coils for MRI-guided interventions.
建立血管内线圈与发射射频激励的感应耦合模型,用于为磁共振成像(MRI)引导的介入操作选择线圈。
针对血管内线圈、电缆、发射激励和成像区域,开发了独立且计算效率高的有限元模型。耦合电磁和电路求解器以模拟净B +场以及感应电流和电压。我们的模型通过用于串联调谐多模线圈的布洛赫 - 西格特B +映射序列进行验证,该序列能够进行跟踪、无线可视化和高分辨率血管内成像。
在实验限制范围内,验证表明在24、28和34 μT背景射频激励下具有良好的一致性。定量的线圈性能指标与模拟结果相符。一项参数研究表明,改变线圈匝数时,线圈性能指标之间存在权衡。在一项猪实验中展示了跟踪、成像和无线标记多模线圈的特征及其集成。
所开发的多模线圈模型得到了成功验证。用于几何优化和线圈选择的建模是耗时且昂贵实验的前奏。展示的具体应用包括参数优化、心脏介入操作的线圈选择以及动物成像实验。
我们模块化、适应性强且计算效率高的建模方法能够快速比较、选择和优化用于MRI引导介入操作的感应耦合线圈。