Ligny C, de Gentile L, Chabasse D, Pineau P, Minckes O, Larget-Piet L
Ann Pediatr (Paris). 1989 Dec;36(10):669-74.
We report a case of congenital malaria due to a chloroquine-resistant strain of Plasmodium falciparum acquired in Mali. Ours is the first report of chloroquine-resistant congenital malaria in this part of Africa. We recall the various pathophysiologic, diagnostic and therapeutic features of this disease that should be considered in every neonate born to a mother who may have malaria. Although such cases are infrequent, we also discuss the very serious problems, mainly therapeutic, that they raise in several countries where they are endemic (South-East Asia and Africa particularly).
我们报告了一例在马里感染耐氯喹恶性疟原虫导致的先天性疟疾病例。我们的报告是非洲该地区首例耐氯喹先天性疟疾报告。我们回顾了这种疾病的各种病理生理、诊断和治疗特征,对于每一位可能感染疟疾的母亲所生的新生儿都应考虑这些特征。尽管此类病例并不常见,但我们也讨论了它们在几个疟疾流行国家(特别是东南亚和非洲)引发的非常严重的问题,主要是治疗方面的问题。