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针刺治疗中重度持续性变应性鼻炎:一项随机对照试验

[Moderate and severe persistent allergic rhinitis treated with acupuncture: a randomized controlled trial].

作者信息

Chen Sheng, Wang Jun, Bai Peng, Zhao Qi, Tan Cheng, Wang Baokai, Zhang Jiaji, Zhao Jiping

出版信息

Zhongguo Zhen Jiu. 2015 Dec;35(12):1209-13.

Abstract

OBJECTIVE

To observe the clinical efficacy and safety on moderate and severe persistent allergic rhinitis treated with acupuncture.

METHODS

Sixty-six patients of moderate and severe persistent allergic rhinitis were randomized into an acupuncture group (34 cases) and a western medication group (32 cases). In the acupuncture, group, acupuncture was applied to Dazhui (GV 14), Feishu (BL 13), Pishu (BL 20), Ganshu (BL 18) and Shenshu (BL 23) in the prone, retained for 20 min; then in the supine, at Baihui (GV 20), Yintang (GV 29), yingxiang (LI20) Taichong (LR 3) and Hegu (LI 4), retained for 20 min. Acupuncture was given once every two days, three times a week, continuously for 8 weeks. In the western medication group, cetirizine hydrochloride was taken orally, 10 mg each time, once every day, continuously for 8 weeks. Separately, before treatment, after the treatment of 1 and 2 months and in 1 month after treatment, the total nasal symptom score (TNSS), the scores in the emotion rating scale for Ganzangxiang of TCM (ERSG) and the rhinoconjunctivitis quality of life questionnaire (RQLQ) were observed in the patients of the two groups. The clinical efficacy was compared between the two groups.

RESULTS

(1) For TNSS, the results after 1 and 2 months treatment and in 1 month after treatment were all, reduced as compare with that before treatment separately in the two groups (P < 0.05, P < 0.01) The result after 2 months treatment was lower than that after 1 month treatment in the acupuncture group (P < 0.05). In 1 month after treatment, the result in the acupuncture group was lower than that in the western medication group (P < 0.05). (2) For ERSG, the score after 2 months treatment was lower than that before treatment in the two groups (both P < 0.05). The score after 2 months treatment in the acupuncture group was lower than that in the western medication group (P < 0.05). (3) For RQLQ, the score after 1 month treatment was lower than that before treatment and the score after 2 months treatment was lower than that after 1 month treatment in the two groups (all P < 0.05). The score after 1 and 2 months treatment and in 1 month after treatment in the acupuncture group was lower than that in the western medication group separately (all P < 0.05). (4) The total effective rate was 91.2% (31/34) in the acupuncture group and was 90.6% (29/32) in the western medication group, without significant difference between the two groups (P > 0.05).

CONCLUSION

Acupuncture is the safe and effective intervention on moderate and severe persistent allergic rhinitis. Compared with the western medicine group, the efficacy in the acupuncture group presents much more advantageous at its durability.

摘要

目的

观察针刺治疗中重度持续性变应性鼻炎的临床疗效及安全性。

方法

将66例中重度持续性变应性鼻炎患者随机分为针刺组(34例)和西药组(32例)。针刺组采用俯卧位针刺大椎(GV 14)、肺俞(BL 13)、脾俞(BL 20)、肝俞(BL 18)、肾俞(BL 23),留针20分钟;然后仰卧位针刺百会(GV 20)、印堂(GV 29)、迎香(LI20)、太冲(LR 3)、合谷(LI 4),留针20分钟。针刺每两天1次,每周3次,连续治疗8周。西药组口服盐酸西替利嗪,每次10mg,每天1次,连续治疗8周。分别观察两组患者治疗前、治疗1个月后、治疗2个月后及治疗后1个月时的总鼻症状评分(TNSS)、中医肝藏象情志量表(ERSG)评分及变应性鼻炎生活质量问卷(RQLQ)评分,并比较两组临床疗效。

结果

(1)TNSS:两组治疗1个月后、治疗2个月后及治疗后1个月时的评分均较治疗前降低(P<0.05,P<0.01);针刺组治疗2个月后的评分低于治疗1个月后的评分(P<0.05);治疗后1个月时,针刺组评分低于西药组(P<0.05)。(2)ERSG:两组治疗2个月后的评分均低于治疗前(均P<0.05);针刺组治疗2个月后的评分低于西药组(P<0.05)。(3)RQLQ:两组治疗1个月后的评分低于治疗前,治疗2个月后的评分低于治疗1个月后的评分(均P<0.05);针刺组治疗1个月后、治疗2个月后及治疗后1个月时的评分均低于西药组(均P<0.05)。(4)针刺组总有效率为91.2%(31/34),西药组为90.6%(29/32),两组比较差异无统计学意义(P>0.05)。

结论

针刺是治疗中重度持续性变应性鼻炎的安全有效干预措施。与西药组比较,针刺组疗效在持久性方面更具优势。

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