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[冬夏温针治疗对变应性鼻炎患者生活质量的影响]

[Impacts on the life quality of the patients with allergic rhinitis treated with warming acupuncture in winter and summer].

作者信息

Xie Yilin, Wan Wenrong, Zhao Yinlong, Ye Zhiying, Chen Huiyang, Hong Xiuyu, Wu Lei, Wang Ruiwen, Yang Jingui

出版信息

Zhongguo Zhen Jiu. 2015 Dec;35(12):1215-20.

Abstract

OBJECTIVE

To explore the impacts on the life quality and the effect mechanism in the patients of allergic rhinitis (AR) treated with warm acupuncture in winter and summer.

METHODS

Two hundred and forty patients of AR were randomized into a summer and winter acupuncture group, a non-summer and winter acupuncture group and a western medication group, 80 cases in each one. In the two acupuncture groups, Dazhui (GV 14), Fengmen (BL 12), Feishu (BL 13), Pishu (BL 20) and Shenshu (BL 23) were selected. In the summer and winter acupuncture group, the warm acupuncture started at the first day of the three periods of hot season and the first day of the third nine-day period after the winter solstice. The treatment was given once every two days, continuously for 15 times. Totally, 30 treatments were required a year. In the non-summer and winter acupuncture group, the warm acupuncture was applied out of the three periods of the hot season and the third nine-day period after the winter solstice. The treatment was given once every two days and 30 treatments for a year. In the western medication group, cetirizine was taken orally, continuously for 30 days as one session. In the three groups, the treatment for 1 year was taken as one session. The second session started in the next year. Totally, 2 sessions were required. The score of rhinoconjunctivitis quality of life questionnaire (RQLQ) and the level of serum immunoglobulin E (IgE) were compared in the patients' of each group before treatment and in 1 and 2 sessions of treatment.

RESULTS

After treatment, the scores of 7 domains, named activities, common complaints, practical problems, sleep, ocular symptoms, nasal symptoms and emotions were all improved as compared with those before treatment, in the patients of the three groups (all P < 0.05). After 2 sessions treatment, the results in the summer and winter acupuncture group were better than those in the other two groups (all P < 0.05), and the results in the non-summer and winter acupuncture group were better than those in the western medication group (all P < 0.05). After treatment, serum IgE level was lower averagely than that before treatment in the three groups (all P < 0.05). After 2 sessions treatment, the result in the summer and winter acupuncture group was lower than that in the other two groups (both P < 0.05), and the result in the non-summer and winter acupuncture group was lower than that in the western medication group (P < 0.05). After treatment, the total effective rate was 92.3% (72/78) in the summer and winter acupuncture group, better than 80.5% (62/77) in the non-summer and winter acupuncture group and 69.7% (53/76) in the western medication group (both P < 0.05).

CONCLUSION

The warm acupuncture in both summer and winter achieves the definite efficacy on AR and the effect mechanism is relevant with reducing serum IgE level.

摘要

目的

探讨冬夏季节温针灸治疗变应性鼻炎(AR)患者对其生活质量的影响及作用机制。

方法

将240例AR患者随机分为冬夏针灸组、非冬夏针灸组和西药组,每组80例。两组针灸组均选取大椎(GV 14)、风门(BL 12)、肺俞(BL 13)、脾俞(BL 20)和肾俞(BL 23)。冬夏针灸组于炎热季节三伏第一天及冬至后三九第一天开始温针灸,每两天治疗1次,连续治疗15次,一年共需治疗30次。非冬夏针灸组于炎热季节三伏及冬至后三九以外的时间进行温针灸,每两天治疗1次,一年治疗30次。西药组口服西替利嗪,连续服用30天为1个疗程。三组均以1年治疗为1个疗程,次年开始第2个疗程,共需治疗2个疗程。比较三组患者治疗前及治疗1个疗程、2个疗程后鼻结膜炎生活质量问卷(RQLQ)评分及血清免疫球蛋白E(IgE)水平。

结果

治疗后,三组患者活动、一般症状、实际问题、睡眠、眼部症状、鼻部症状及情绪7个领域的评分均较治疗前改善(均P < 0.05)。治疗2个疗程后,冬夏针灸组各项结果均优于其他两组(均P < 0.05),非冬夏针灸组各项结果优于西药组(均P < 0.05)。治疗后,三组患者血清IgE水平均较治疗前平均降低(均P < 0.05)。治疗2个疗程后,冬夏针灸组血清IgE水平低于其他两组(均P < 0.05),非冬夏针灸组低于西药组(P < 0.05)。治疗后,冬夏针灸组总有效率为92.3%(72/78),优于非冬夏针灸组的80.5%(62/77)和西药组的69.7%(53/76)(均P < 0.05)。

结论

冬夏季节温针灸治疗AR疗效确切,其作用机制与降低血清IgE水平有关。

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