Josten Christoph, Jarvers Jan-Sven, Glasmacher Stefan, Heyde Christoph-Eckhard, Spiegl Ulrich J
Department of Orthopaedics, Trauma and Plastic Surgery, Spine Center, University of Leipzig, Liebigstr. 20, 04103, Leipzig, Germany.
Eur Spine J. 2016 Jul;25(7):2210-7. doi: 10.1007/s00586-016-4493-5. Epub 2016 Mar 10.
The purpose of this study was to evaluate the 1-year outcome after anterior transarticular atlantoaxial fixation and odontoid fusion (TAFOF) for type II odontoid fractures and atlanto-odontoid osteoarthritis (AO) in elderly patients.
All geriatric patients, age 70 or older, with acute traumatic type II odontoid fractures and moderate or severe AO treated by TAFOF were included. The study was performed at a single institution between June 2008 and August 2013. Patients were evaluated clinically and radiologically after 1 year. Main parameter of interest were in-hospital and 1-year mortality rates, complication rates (re-operations, prolonged hospital stay, blood transfusion; non-union), and the patients' pain (0: no pain; 10: maximal pain) and satisfaction level (0: lowest satisfaction; 10: highest satisfaction) after 1 year.
A total of 83 patients were included with an average age of 84.7 years (range 70-101 years). 39 patients were subdivided as "old" with an age 70-84 years and 44 patients were defined as "very old" with an age of 85 or higher. The average operation time was 64.7 min. Three patients died during the inpatient stay (3.6 %). Twenty patients (24.1 %) were lost contact follow-up. The 1-year mortality was 25.4 % with a significantly higher mortality rate in very old patient group (p = 0.01). At the 1-year follow-up, the mean pain level was 3.3 and the mean patient satisfaction level was 6.5. Osseous consolidation of the dens was visible in 90.2 % of patients. Revision surgery was performed in three patients (3.6 %). Generally, a significantly higher complication rate was seen after single-screw fixation of the dens compared to a double-screw fixation in combination with TAF (p = 0.042).
Anterior TAFOF leads to promising 1-year results with low in-hospital mortality and a high fusion rate in geriatric patients with type II odontoid fractures and relevant AO. Double-screw dens fixation seems to reduce the complication rate.
本研究旨在评估老年患者Ⅱ型齿状突骨折和寰枢椎骨关节炎(AO)行前路经关节寰枢椎固定及齿状突融合术(TAFOF)后的1年疗效。
纳入所有年龄在70岁及以上、因急性创伤性Ⅱ型齿状突骨折和中度或重度AO接受TAFOF治疗的老年患者。本研究于2008年6月至2013年8月在单一机构进行。患者在1年后接受临床和影像学评估。主要观察指标包括住院期间及1年死亡率、并发症发生率(再次手术、住院时间延长、输血;骨不连),以及患者1年后的疼痛程度(0:无疼痛;10:最剧烈疼痛)和满意度(0:最低满意度;10:最高满意度)。
共纳入83例患者,平均年龄84.7岁(范围70 - 101岁)。39例患者被分为“老年”组,年龄70 - 84岁,44例患者被定义为“高龄”组,年龄85岁及以上。平均手术时间为64.7分钟。3例患者在住院期间死亡(3.6%)。20例患者(24.1%)失访。1年死亡率为25.4%,高龄患者组死亡率显著更高(p = 0.01)。在1年随访时,平均疼痛程度为3.3,平均患者满意度为6.5。90.2%的患者可见齿状突骨融合。3例患者(3.6%)接受了翻修手术。一般来说,与双螺钉固定联合TAF相比,单螺钉固定齿状突后的并发症发生率显著更高(p = 0.042)。
前路TAFOF在老年Ⅱ型齿状突骨折和相关AO患者中可取得较好的1年疗效,住院死亡率低,融合率高。双螺钉齿状突固定似乎可降低并发症发生率。