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标准经皮肾镜取石术与无管微通道经皮肾镜取石术:一项随机对照试验。

Standard versus tubeless mini-percutaneous nephrolithotomy: A randomised controlled trial.

作者信息

Sebaey Ahmed, Khalil Mostafa M, Soliman Tarek, Mohey Ahmed, Elshaer Walid, Kandil Wael, Omar Rabea

机构信息

Department of Urology, Faculty of Medicine, Benha University, Benha, Egypt.

出版信息

Arab J Urol. 2016 Mar;14(1):18-23. doi: 10.1016/j.aju.2015.11.005. Epub 2016 Jan 20.

Abstract

OBJECTIVE

To prospectively compare the outcome of standard mini-percutaneous nephrolithotomy (SmPCNL) versus tubeless mini-percutaneous nephrolithotomy (TmPCNL) as primary treatments of renal stones.

PATIENTS AND METHODS

In all, 80 patients with a solitary radio-opaque renal stone and candidates for PCNL were selected. The patients were randomly divided into two groups of 40, one group treated with SmPCNL and the other with TmPCNL. Patients and stone characters, as well as operative and postoperative data of both groups were compared and statistically analysed.

RESULTS

There was no significant difference between the two groups for patient demographics and stone characteristics. There was no statistically significant difference between the two groups for the mean operative time, mean postoperative drop in haemoglobin, mean postoperative urine leakage, mean hospital stay, and stone-free rate. The mean (SD) postoperative dose of analgesia was statistically significantly higher in the SmPCNL group compared with the TmPCNL group, at 112.5 (48.03) versus 48.8 (43.5) mg, respectively.

CONCLUSION

Both procedures are safe and effective for managing renal stones, without any significant difference between the two procedures; however, the postoperative analgesic requirement is significantly higher in SmPCNL.

摘要

目的

前瞻性比较标准微创经皮肾镜取石术(SmPCNL)与无管微创经皮肾镜取石术(TmPCNL)作为肾结石主要治疗方法的疗效。

患者与方法

共选取80例有单个不透X线肾结石且适合行经皮肾镜取石术的患者。将患者随机分为两组,每组40例,一组接受SmPCNL治疗,另一组接受TmPCNL治疗。比较两组患者及结石特征,以及手术和术后数据,并进行统计学分析。

结果

两组患者的人口统计学特征和结石特点无显著差异。两组的平均手术时间、术后血红蛋白平均下降值、术后平均尿漏、平均住院时间和结石清除率无统计学显著差异。SmPCNL组术后平均(标准差)镇痛剂量为112.5(48.03)mg,TmPCNL组为48.8(43.5)mg,SmPCNL组在统计学上显著高于TmPCNL组。

结论

两种手术方法治疗肾结石均安全有效,两者之间无任何显著差异;然而,SmPCNL术后镇痛需求显著更高。

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