Kawada Chinatsu, Kimura Mamoru, Masuda Yasunobu, Nomura Yoshihiro
a R&D Division , Kewpie Corporation , Chofu-shi, Tokyo , Japan.
b Laboratory of Applied Protein Chemistry, Faculty of Agriculture , Tokyo University of Agriculture and Technology , Fuchu-shi, Tokyo , Japan.
Biosci Biotechnol Biochem. 2016 Jun;80(6):1192-5. doi: 10.1080/09168451.2016.1146065. Epub 2016 Mar 11.
The oral administration of hyaluronans (HAs) (molecular weight, 300k and less than 10k) to photoaged hairless mice increased the moisture content of the stratum corneum and decreased the epidermal thickness, respectively. Furthermore, orally administered HAs suppressed the low-molecular weight of HA content of the skin. This study indicates oral administered HAs may ameliorate the skin condition resulting from photoaging.
向光老化无毛小鼠口服透明质酸（HAs）（分子量为300k及小于10k），分别增加了角质层的水分含量并降低了表皮厚度。此外，口服HAs抑制了皮肤中低分子量HA的含量。本研究表明，口服HAs可能改善光老化导致的皮肤状况。
