Felix R, Zwicker C, Zwicker D
Fortschr Ophthalmol. 1989;86(6):636-8.
Today the best radiotherapeutic procedure for treating small choroidal melanomas involves the application of rhutenium 106, thereby sparing the bulbus, or application of iodine 125 in larger tumors. In extensive tumors, the additional use of local hyperthermia promises further enhancement of brachytherapy with applicators. In the foreseeable future, therapeutic concepts primarily for the palliative treatment of advanced, metastasing melanomas might include the use of antimetabolites or therapy with monoclonal radioactively changed antibodies.
如今,治疗小脉络膜黑色素瘤的最佳放射治疗方法是应用钌106,从而保留眼球,或在较大肿瘤中应用碘125。对于广泛的肿瘤,额外使用局部热疗有望通过施源器进一步增强近距离放射治疗效果。在可预见的未来,主要用于晚期转移性黑色素瘤姑息治疗的治疗理念可能包括使用抗代谢物或用单克隆放射性改变抗体进行治疗。