Muller R P, Busse H, Kroll P, Gast E
J Fr Ophtalmol. 1985;8(10):639-43.
Recently, enucleation of choroidal melanomas tends to be replaced by less radical treatments such as photocoagulation. Use of Ruthenium 106 plaques has proved to be efficient in Germany. Because the Beta rays of Ruthenium 106 have only limited tissue penetration they are used only for tumors of less than 6-7 mm thickness and less than 18 mm2 surface. This report describes 62 cases of choroidal melanomas treated with Ruthenium 106. With a follow-up period of 12 to 48 months, 32 cases had total regression, including 2 cases with metastases. 15 patients required a second procedue and 15 had additional photocoagulation. In 23 of 51 patients the visual acuity remained unchanged. In 26 patients the visual acuity decreased and 2 patients had an improvement. 13 patients with melanomas inside or close to the macular area decreased their visual acuity.
最近，脉络膜黑色素瘤的眼球摘除术往往被诸如光凝等不太激进的治疗方法所取代。在德国，使用钌106敷贴器已被证明是有效的。由于钌106的β射线组织穿透性有限，它们仅用于厚度小于6 - 7毫米且表面积小于18平方毫米的肿瘤。本报告描述了62例用钌106治疗的脉络膜黑色素瘤病例。随访期为12至48个月，32例完全消退，其中包括2例有转移的病例。15例患者需要二次手术，15例进行了额外的光凝治疗。51例患者中有23例视力保持不变。26例患者视力下降，2例患者视力改善。13例黄斑区或靠近黄斑区有黑色素瘤的患者视力下降。
