Witschel H
Fortschr Ophthalmol. 1989;86(6):738-43.
The histopathology of the eye is especially suitable for demonstrating the necessity and advantages of a close clinicopathological correlation. It should therefore be performed by a clinical ophthalmologist who is especially trained in histopathology. During recent years it has been realized more and more that metabolism and function in a living organism are only possible in relation to intact morphological structures. This led to a "renaissance" of morphology in general and of human histopathology and ophthalmopathology in particular. The workup of ophthalmopathologic specimens includes careful dissection of the globe, its macroscopic examination under the stereomicroscope, photographic documentation of interesting findings, and the application of all modern techniques of histopathology, such as light microscopy, electron microscopy, scanning electron microscopy, freeze-fracture techniques, and immunohistochemistry. The above methods are briefly discussed.
眼部组织病理学特别适合用于证明临床病理密切关联的必要性和优势。因此,应由经过组织病理学专门培训的临床眼科医生来进行此项操作。近年来,人们越来越意识到,生物体中的新陈代谢和功能只有在完整的形态结构基础上才有可能实现。这导致了形态学的“复兴”,尤其是人体组织病理学和眼科病理学。眼科病理标本的处理包括对眼球进行仔细解剖、在体视显微镜下进行宏观检查、对有趣的发现进行摄影记录,以及应用所有现代组织病理学技术,如光学显微镜检查、电子显微镜检查、扫描电子显微镜检查、冷冻断裂技术和免疫组织化学。以下将对上述方法进行简要讨论。