Joseph Natalie Pierre, Bernstein Judith, Pelton Steve, Belizaire Myrdell, Goff Ginette, Horanieh Nour, Freund Karen M
Boston University, Boston, MA, USA
Boston University, Boston, MA, USA.
Clin Pediatr (Phila). 2016 Aug;55(9):851-9. doi: 10.1177/0009922815616244. Epub 2016 Mar 10.
Objective To evaluate the impact of a client-centered behavioral intervention (Brief Negotiated Interviewing) on mothers' human papillomavirus (HPV) vaccine knowledge and vaccination initiation for their adolescent daughters. Methods We randomized mothers to intervention (n = 100) and control (n = 100) groups, and followed them over 12 months. Electronic medical records were reviewed to determine vaccination status. The primary outcome was receipt of the first vaccine. The secondary outcome was HPV vaccine knowledge among mothers. Results Brief Negotiated Interviewing intervention mothers demonstrated increased knowledge about HPV (pre/post mean score of 5 to 10 out of a possible 11; P < .001) and significantly higher mean knowledge scores (10 vs 6, P < .001) than control mothers. However, initiation and completion rates of the vaccine were not significantly different between groups. Conclusions Increasing HPV vaccine knowledge did not translate into increased vaccine uptake or completion of vaccination series. Future intervention must explore vaccine reminders to increase HPV vaccination rates.
目的 评估以客户为中心的行为干预措施（简短协商访谈）对母亲们关于人乳头瘤病毒（HPV）疫苗的知识以及其青春期女儿HPV疫苗接种起始情况的影响。方法 我们将母亲们随机分为干预组（n = 100）和对照组（n = 100），并对她们进行了为期12个月的随访。通过查阅电子病历确定疫苗接种状况。主要结局指标是首次接种疫苗的情况。次要结局指标是母亲们的HPV疫苗知识。结果 接受简短协商访谈干预的母亲们对HPV的知识有所增加（可能得分为11分的情况下，干预前/后平均得分从5分提高到10分；P < .001），且平均知识得分显著高于对照组母亲（10分对6分，P < .001）。然而，两组之间疫苗的起始接种率和完成接种率并无显著差异。结论 HPV疫苗知识的增加并未转化为疫苗接种率的提高或接种系列的完成。未来的干预措施必须探索疫苗提醒方式以提高HPV疫苗接种率。
