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新型隐球菌临床分离株对5-氟胞嘧啶的耐药性

5-Fluorocytosine resistance in clinical isolates of Cryptococcus neoformans.

作者信息

Chin C S, Cheong Y M, Wong Y H

出版信息

Med J Malaysia. 1989 Sep;44(3):194-8.

PMID:2696871
Abstract

Thirty six clinical isolates of Cryptococcus neoformans were tested for their susceptibility to 5-fluorocytosine and amphotericin B by the determination of minimum inhibitory concentrations and minimum fungicidal concentrations. 22.2% of the isolates were resistant to 5-fluorocytosine and 36.1% indicated 5-fluorocytosine tolerance. All strains were sensitive to amphotericin B.

摘要

通过测定最低抑菌浓度和最低杀菌浓度,对36株新型隐球菌临床分离株进行了5-氟胞嘧啶和两性霉素B的药敏试验。22.2%的分离株对5-氟胞嘧啶耐药,36.1%表现出对5-氟胞嘧啶耐受。所有菌株对两性霉素B敏感。

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