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Bio-engineered and native red blood cells from cord blood exhibit the same metabolomic profile.生物工程改造的脐带血红细胞与天然脐带血红细胞具有相同的代谢组学特征。
Haematologica. 2016 Jun;101(6):e220-2. doi: 10.3324/haematol.2015.141465. Epub 2016 Mar 11.
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New ways to count CD34.计数CD34的新方法。
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Plasma-depleted versus red cell-reduced umbilical cord blood.血浆去除型与红细胞减少型脐带血。
Cell Transplant. 2014;23(4-5):407-15. doi: 10.3727/096368914X678481.
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Cargo-encapsulated cells for drug delivery.用于药物递送的载有货物的细胞。
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Umbilical Cord Blood-Derived Mononuclear Cells Exhibit Pericyte-Like Phenotype and Support Network Formation of Endothelial Progenitor Cells In Vitro.脐血来源的单个核细胞表现出类周细胞表型并在体外支持内皮祖细胞的网络形成。
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Comparative study of antioxidant enzymes and lipid peroxidation in cord and maternal red blood cells.脐带血与母体红细胞中抗氧化酶及脂质过氧化的比较研究
Acta Paediatr Hung. 1990;30(3-4):391-7.
7
Quality and stability of red cells derived from gravity-separated placental blood with a hollow-fiber system.采用中空纤维系统从重力分离的胎盘血中获取的红细胞的质量和稳定性。
Transfusion. 2007 Dec;47(12):2271-5. doi: 10.1111/j.1537-2995.2007.01456.x. Epub 2007 Aug 21.
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Osmotic parameters of red blood cells from umbilical cord blood.脐带血红细胞的渗透参数。
Cryobiology. 2014 Jun;68(3):379-88. doi: 10.1016/j.cryobiol.2014.04.002. Epub 2014 Apr 12.
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Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells.人类遗传变异的靶向应用可改善干细胞产生红细胞的能力。
Cell Stem Cell. 2016 Jan 7;18(1):73-78. doi: 10.1016/j.stem.2015.09.015. Epub 2015 Oct 22.
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Rabbit IgG antibodies against cord red blood cell membranes bind to complement receptor 1 (CD35).针对脐带红细胞膜的兔IgG抗体与补体受体1(CD35)结合。
Acta Haematol. 1998 Dec;100(3):123-9. doi: 10.1159/000040886.

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Initial investigation on the feasibility of porcine red blood cells from genetically modified pigs as an alternative to human red blood cells for transfusion.初步研究用基因修饰猪的猪红细胞替代人红细胞用于输血的可行性。
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The biology of ergothioneine, an antioxidant nutraceutical.ergothioneine 的生物学特性,一种抗氧化的营养保健品。
Nutr Res Rev. 2020 Dec;33(2):190-217. doi: 10.1017/S0954422419000301. Epub 2020 Feb 13.
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PIEZO1 gain-of-function mutations delay reticulocyte maturation in hereditary xerocytosis.PIEZO1功能获得性突变会延迟遗传性口形红细胞增多症中网织红细胞的成熟。
Haematologica. 2020 Jun;105(6):e268-e271. doi: 10.3324/haematol.2019.231159. Epub 2019 Oct 17.
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Genetically-engineered pigs as sources for clinical red blood cell transfusion: What pathobiological barriers need to be overcome?基因工程猪作为临床红细胞输血的来源:需要克服哪些病理生物学障碍?
Blood Rev. 2019 May;35:7-17. doi: 10.1016/j.blre.2019.01.003. Epub 2019 Jan 28.
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Non-muscle myosin II drives vesicle loss during human reticulocyte maturation.非肌球蛋白 II 驱动人网织红细胞成熟过程中的囊泡丢失。
Haematologica. 2018 Dec;103(12):1997-2007. doi: 10.3324/haematol.2018.199083. Epub 2018 Aug 3.
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A Novel High-Throughput Screening Platform Reveals an Optimized Cytokine Formulation for Human Hematopoietic Progenitor Cell Expansion.一种新型高通量筛选平台揭示了用于人类造血祖细胞扩增的优化细胞因子配方。
Stem Cells Dev. 2016 Nov 15;25(22):1709-1720. doi: 10.1089/scd.2016.0216. Epub 2016 Sep 30.

本文引用的文献

1
Annotation of the human serum metabolome by coupling three liquid chromatography methods to high-resolution mass spectrometry.通过将三种液相色谱方法与高分辨率质谱联用对人血清代谢组进行注释。
J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Sep 1;966:34-47. doi: 10.1016/j.jchromb.2014.04.025. Epub 2014 Apr 21.
2
Significant biochemical, biophysical and metabolic diversity in circulating human cord blood reticulocytes.人脐血网织红细胞中存在显著的生化、生物物理和代谢多样性。
PLoS One. 2013 Oct 8;8(10):e76062. doi: 10.1371/journal.pone.0076062. eCollection 2013.
3
Proof of principle for transfusion of in vitro-generated red blood cells.体外生成红细胞输注的原理验证。
Blood. 2011 Nov 10;118(19):5071-9. doi: 10.1182/blood-2011-06-362038. Epub 2011 Sep 1.
4
Alterations of red blood cell metabolome in overhydrated hereditary stomatocytosis.红细胞代谢组在遗传性水肿性口腔炎中的改变。
Haematologica. 2011 Dec;96(12):1861-5. doi: 10.3324/haematol.2011.045179. Epub 2011 Aug 22.
5
Normal and disordered reticulocyte maturation.正常和异常网织红细胞成熟。
Curr Opin Hematol. 2011 May;18(3):152-7. doi: 10.1097/MOH.0b013e328345213e.
6
Pathophysiology of sickle cell disease is mirrored by the red blood cell metabolome.镰状细胞病的病理生理学反映在红细胞代谢组学中。
Blood. 2011 Feb 10;117(6):e57-66. doi: 10.1182/blood-2010-07-299636. Epub 2010 Dec 6.
7
Metabolomic analysis of normal and sickle cell erythrocytes.正常和镰状红细胞的代谢组学分析。
Transfus Clin Biol. 2010 Sep;17(3):148-50. doi: 10.1016/j.tracli.2010.06.011. Epub 2010 Jul 31.
8
Ex vivo production of human red blood cells from hematopoietic stem cells: what is the future in transfusion?从造血干细胞体外生产人类红细胞:输血的未来何在?
Transfus Med Rev. 2007 Apr;21(2):91-100. doi: 10.1016/j.tmrv.2006.11.004.
9
Discovery of the ergothioneine transporter.麦角硫因转运体的发现。
Proc Natl Acad Sci U S A. 2005 Apr 5;102(14):5256-61. doi: 10.1073/pnas.0408624102. Epub 2005 Mar 28.
10
Ex vivo generation of fully mature human red blood cells from hematopoietic stem cells.从造血干细胞体外生成完全成熟的人类红细胞。
Nat Biotechnol. 2005 Jan;23(1):69-74. doi: 10.1038/nbt1047. Epub 2004 Dec 26.

Bio-engineered and native red blood cells from cord blood exhibit the same metabolomic profile.

作者信息

Darghouth Dhouha, Giarratana Marie-Catherine, Oliveira Lydie, Jolly Séverine, Marie Tiffany, Boudah Samia, Mario Nathalie, Junot Christophe, Douay Luc, Romeo Paul-Henri

机构信息

Sorbonne Universités, UPMC Univ Paris 06, Inovarion, Inserm UMRS 938, Centre de Recherche Saint-Antoine, Paris 7, France

Sorbonne Universités, UPMC Univ Paris 06, Inserm UMRS 938, Centre de Recherche Saint-Antoine, Paris 7, France.

出版信息

Haematologica. 2016 Jun;101(6):e220-2. doi: 10.3324/haematol.2015.141465. Epub 2016 Mar 11.

DOI:10.3324/haematol.2015.141465
PMID:26969083
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5013952/
Abstract
摘要